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Report error Found 565 for UniProtKB: A2I2P7
TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410826BDBM410826(US10383880, Example 38)
Affinity DataEC50:  11nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410874BDBM410874(US10383880, Example 87)
Affinity DataEC50:  20nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410827BDBM410827(US10383880, Example 39)
Affinity DataEC50:  21nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410907BDBM410907(US10383880, Example 120)
Affinity DataEC50:  23nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410959BDBM410959(US10383880, Example 171)
Affinity DataEC50:  25nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410931BDBM410931(US10383880, Example 143)
Affinity DataEC50:  28nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 50140888BDBM50140888(CHEMBL3753839 | US10383880, Example 20)
Affinity DataEC50:  29nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410822BDBM410822(US10383880, Example 34)
Affinity DataEC50:  31nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410883BDBM410883(US10383880, Example 100 | US10383880, Example 96)
Affinity DataEC50:  32nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 50140893BDBM50140893(CHEMBL3753932 | US10383880, Example 123)
Affinity DataEC50:  33nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410825BDBM410825(US10383880, Example 37)
Affinity DataEC50:  34nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 50140922BDBM50140922(CHEMBL3752819 | US10383880, Example 57)
Affinity DataEC50:  35nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410963BDBM410963(US10383880, Example 175)
Affinity DataEC50:  35nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 50140889BDBM50140889(CHEMBL3752502 | US10383880, Example 33)
Affinity DataEC50:  35nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410906BDBM410906(US10383880, Example 119)
Affinity DataEC50:  37nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410879BDBM410879(US10383880, Example 92)
Affinity DataEC50:  40nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410925BDBM410925(US10383880, Example 138)
Affinity DataEC50:  41nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 411033BDBM411033(US10383880, Example 243)
Affinity DataEC50:  42nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 50140891BDBM50140891(CHEMBL3753487)
Affinity DataEC50:  42nMAssay Description:Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythmsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410899BDBM410899(US10383880, Example 112)
Affinity DataEC50:  44nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410973BDBM410973(US10383880, Example 185)
Affinity DataEC50:  45nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410873BDBM410873(US10383880, Example 86)
Affinity DataEC50:  46nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410888BDBM410888(US10383880, Example 101)
Affinity DataEC50:  50nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410908BDBM410908(US10383880, Example 121)
Affinity DataEC50:  51nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356927BDBM356927(1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...)
Affinity DataEC50:  52nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356927BDBM356927(1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...)
Affinity DataEC50:  52nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410971BDBM410971(US10383880, Example 183)
Affinity DataEC50:  53nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356720BDBM356720((1R,4S)-2-((R)-3- (3,6-difluoro-9H- carbazol-9-yl)...)
Affinity DataEC50:  54nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356720BDBM356720((1R,4S)-2-((R)-3- (3,6-difluoro-9H- carbazol-9-yl)...)
Affinity DataEC50:  54nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 411034BDBM411034(US10383880, Example 244)
Affinity DataEC50:  57nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 411014BDBM411014(US10383880, Example 224)
Affinity DataEC50:  59nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356634BDBM356634(1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl)-3- fluo...)
Affinity DataEC50:  61nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356634BDBM356634(1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl)-3- fluo...)
Affinity DataEC50:  61nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410966BDBM410966(US10383880, Example 178)
Affinity DataEC50:  73nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 50140890BDBM50140890(CHEMBL3754594)
Affinity DataEC50:  73nMAssay Description:Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythmsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410924BDBM410924(US10383880, Example 137)
Affinity DataEC50:  76nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410984BDBM410984(US10383880, Example 194)
Affinity DataEC50:  78nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356696BDBM356696(1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...)
Affinity DataEC50:  79nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410918BDBM410918(US10383880, Example 131)
Affinity DataEC50:  79nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356696BDBM356696(1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...)
Affinity DataEC50:  79nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410962BDBM410962(US10383880, Example 174)
Affinity DataEC50:  80nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410905BDBM410905(US10383880, Example 118)
Affinity DataEC50:  81nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410974BDBM410974(US10383880, Example 186)
Affinity DataEC50:  83nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410898BDBM410898(US10383880, Example 111)
Affinity DataEC50:  84nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410961BDBM410961(US10383880, Example 173)
Affinity DataEC50:  86nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356724BDBM356724((1R,4S)-2-((R)-3- (9H-carbazol-9-yl)- 2-hydroxypro...)
Affinity DataEC50:  89nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356724BDBM356724((1R,4S)-2-((R)-3- (9H-carbazol-9-yl)- 2-hydroxypro...)
Affinity DataEC50:  89nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 50140765BDBM50140765(CHEMBL1446115 | US10383880, Example 23)
Affinity DataEC50:  90nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 410953BDBM410953(US10383880, Example 165)
Affinity DataEC50:  95nMAssay Description:Per2 Assay for Evaluating the Potency of Test Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Synchronicity

US Patent
LigandChemical structure of BindingDB Monomer ID 356922BDBM356922((R)-1-((R)-3-(9H- carbazol-9-yl)-2- hydroxypropyl)...)
Affinity DataEC50:  95nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

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