Compile Data Set for Download or QSAR
Report error Found 1251 of affinity data for UniProtKB/TrEMBL: P00735
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029090(CHEMBL3343301)
Affinity DataKi:  0.0960nMAssay Description:Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50291355(1-[3-[4-amino(amineimino)methylphenyl]-2-(2-anthry...)
Affinity DataKi:  1nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50098235(3-[4-(Amino-hydrazino-methyl)-phenyl]-N-cyclopenty...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity was determined against bovine thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50069294(1N-cyclopentyl-3-[4-amino(aminoimino)methylphenyl]...)
Affinity DataKi:  1.10nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50098236(Naphthalene-2-sulfonic acid {1-[4-(amino-hydrazino...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity was determined against bovine thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50069297(1-[3-[4-amino(amineimino)methylphenyl]-2-(2-naphth...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060017(3-[(R)-3-(4-Methanesulfonyl-piperazin-1-yl)-2-(nap...)
Affinity DataKi:  2.10nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060036(3-[(R)-3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-...)
Affinity DataKi:  2.5nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060014(3-[3-(4-Methanesulfonyl-piperazin-1-yl)-2-(naphtha...)
Affinity DataKi:  3.30nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060052(3-[(S)-3-(4-Methanesulfonyl-piperazin-1-yl)-2-(nap...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50069292(N-ethyl-N-cyclopentyl-3-(4-hydrazonoformamidepheny...)
Affinity DataKi:  4nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50472462(CHEMBL145664)
Affinity DataKi:  4.20nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060027(3-[2-(4-tert-Butyl-benzenesulfonylamino)-3-(4-meth...)
Affinity DataKi:  4.30nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50472496(CHEMBL358110)
Affinity DataKi:  4.30nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50472467(CHEMBL344552)
Affinity DataKi:  5nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060019(3-[(R)-3-(4-Methanesulfonyl-piperazin-1-yl)-3-oxo-...)
Affinity DataKi:  5.30nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50082611(3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfon...)
Affinity DataKi:  5.70nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442068(CHEMBL2441057)
Affinity DataKi:  6nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50037996(N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50037996(N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-...)
Affinity DataKi:  6nMAssay Description:Inhibitory Activity against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50072840(N-[1-(4-Diaminomethyl-benzyl)-2-oxo-2-piperidin-1-...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against bovine thrombin expressed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442068(CHEMBL2441057)
Affinity DataKi:  6nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50082575(3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfon...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50472473(CHEMBL358970)
Affinity DataKi:  6.20nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  6.20nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  6.20nMAssay Description:Inhibitory activity against bovine thrombin expressed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50098230(N-[1-(4-Diaminomethyl-benzyl)-2-oxo-2-piperidin-1-...)
Affinity DataKi:  6.5nMAssay Description:Binding affinity was determined against bovine thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50037996(N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-...)
Affinity DataKi:  6.5nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50082578(6-Chloro-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline...)
Affinity DataKi:  6.60nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50472505(CHEMBL141782)
Affinity DataKi:  7.40nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060039(3-[3-(4-Methanesulfonyl-piperazin-1-yl)-3-oxo-2-(2...)
Affinity DataKi:  7.40nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060045(4-[(S)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060056(4-[3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2-sul...)
Affinity DataKi:  8.80nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50228863(1-(2-Methylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataIC50: 8.90nMAssay Description:In vitro Enzyme Inhibitory activity measured against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50038001(CHEMBL1166 | (2R,4S)-1-[5-Guanidino-2-(3-methyl-1,...)
Affinity DataKi:  9.60nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029498(1N-[2-{2-[4-amino(imino)methylamino-1-formyl-(1S)-...)
Affinity DataIC50: 9.60nMAssay Description:In vitro Enzyme Inhibitory activity measured against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50082579(6-Chloro-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060029(3-[(R)-3-(4-Acetyl-piperazin-1-yl)-2-(naphthalene-...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060054(3-[2-[2-(7,7-Dimethyl-2-oxo-bicyclo[2.2.1]hept-1-y...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060046(3-[(R)-2-[2-(7,7-Dimethyl-2-oxo-bicyclo[2.2.1]hept...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50592215(CHEMBL5205860)
Affinity DataKi:  12nMAssay Description:Binding affinity to bovine thrombin assessed as inhibition constant using tosyl-Gly-Pro-Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50472517(CHEMBL342722)
Affinity DataKi:  13nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029510(1N-[2-{2-[4-amino(imino)methylamino-1-formyl-(1S)-...)
Affinity DataIC50: 13nMAssay Description:In vitro Enzyme Inhibitory activity measured against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50269544(tellimagrandin II | CHEMBL510512)
Affinity DataIC50: 14nMAssay Description:Inhibition of bovine thrombin-catalyzed hydrolysis of fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50472477(CHEMBL357210)
Affinity DataKi:  14nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50082583(Acetic acid 2-{1-[5-guanidino-2-(3-methyl-1,2,3,4-...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50060031(3-[(R)-3-(4-Methyl-piperazin-1-yl)-2-(naphthalene-...)
Affinity DataKi:  16nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029506(tert-butyloxy carbonyl-D-ethylphenylglycine-Pro-Ar...)
Affinity DataIC50: 16nMAssay Description:In vitro Enzyme Inhibitory activity measured against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50472502(CHEMBL358081)
Affinity DataKi:  16nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
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