Compile Data Set for Download or QSAR
Report error Found 97 of affinity data for UniProtKB/TrEMBL: P16233
LigandPNGBDBM50212744(TRIBUTYRIN | CHEBI:35020)
Affinity DataKi: <1nM Kon:  1M-1s-1Assay Description:Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase), 1.5 ug/mL of colipase and 4 mM sodium taurodeoxycholatet (NaTDC) at a compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 1.60nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human PL expressed in HEK293F cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 33nMAssay Description:Inhibition of pancreatic lipase (unknown origin) by spectrophotometeric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 80.7nMAssay Description:Inhibition of pancreatic lipase assessed as umoles of oleic acic released per millimiter of triolein per hourMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50212746(CHEMBL119630)
Affinity DataKi:  220nM Kon:  220M-1s-1Assay Description:Tested for hydrolysis with 0.5 ug/mL of PPL (porcine pancreatic lipase), 1.5 ug/mL of colipase and 4 mM of sodium taurodeoxycholatet (NaTDC) at the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 490nMAssay Description:Inhibition of Pancreatic lipase (unknown origin) using 4-MUO as fluorescent substrate preincubated for 3 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50212746(CHEMBL119630)
Affinity DataKi:  710nM Kon:  710M-1s-1Assay Description:Tested for hydrolysis with 1.0 ug/mL of PPL (porcine pancreatic lipase), 2.2 ug/mL of colipase and 4 mM of sodium taurodeoxycholatet (NaTDC) at the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 780nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 806nMAssay Description:Compound was tested for inhibition of porcine pancreatic lipaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
LigandPNGBDBM50367145(CHEMBL4173252)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50212744(TRIBUTYRIN | CHEBI:35020)
Affinity DataKi:  1.10E+3nM Kon:  1.10E+3M-1s-1Assay Description:Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase) at a compound dose of 0.2 gMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

LigandPNGBDBM50367138(CHEMBL4160519)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50625716(CHEMBL5416736)
Affinity DataKi:  1.29E+3nMAssay Description:Binding affinity to pancreatic lipase (unknown origin) assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 1.34E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.53E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50560416(CHEMBL4641560)
Affinity DataIC50: 1.63E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50367133(CHEMBL4164998)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50618931(CHEMBL5410259)
Affinity DataKi:  1.67E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase assessed as inhibition of PL-mediated DDAO-ol hydrolysis by measuring inhibition co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50560416(CHEMBL4641560)
Affinity DataKi:  1.70E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase assessed as inhibition of PL-mediated DDAO-ol hydrolysis by measuring inhibition co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50618931(CHEMBL5410259)
Affinity DataIC50: 1.86E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50367134(CHEMBL4167341)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50625716(CHEMBL5416736)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of pancreatic lipase (unknown origin) by spectrophotometeric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM50367211(CHEMBL4165339)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50212746(CHEMBL119630)
Affinity DataKi:  2.10E+3nM Kon:  2.10E+3M-1s-1Assay Description:Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase) at the compound dose of 0.2 gMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

LigandPNGBDBM50569167(CHEMBL4847734)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
LigandPNGBDBM50618932(CHEMBL1631675)
Affinity DataIC50: 2.13E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50367212(CHEMBL4168413)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50367214(CHEMBL4163899)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50022832(Rafoxanide)
Affinity DataIC50: 2.52E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50614084(CHEMBL4128298)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of pancreatic lipase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM50232349(CHEMBL4102155)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human pancreatic lipase using 4-methylumbelliferyl oleate as substrate after 30 mins by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50179008(sanggenon C | CHEMBL204813)
Affinity DataIC50: 3.28E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50215413(CHEMBL360443)
Affinity DataIC50: 3.44E+3nMAssay Description:Compound was tested for inhibition of porcine pancreatic lipaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
LigandPNGBDBM50569165(CHEMBL4856331)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
LigandPNGBDBM50618929(CHEMBL5423733)
Affinity DataIC50: 4.27E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50569166(CHEMBL4860907)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
LigandPNGBDBM50212746(CHEMBL119630)
Affinity DataKi:  5.70E+3nM Kon:  5.70E+3M-1s-1Assay Description:Tested for hydrolysis with 1.0 ug/mL of PPL (porcine pancreatic lipase)at the compound dose of 0.2 gMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

LigandPNGBDBM50569168(CHEMBL4847071)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
LigandPNGBDBM50618927(CHEMBL5419885)
Affinity DataIC50: 5.99E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50625713(CHEMBL5425089)
Affinity DataIC50: 6.15E+3nMAssay Description:Inhibition of pancreatic lipase (unknown origin) by spectrophotometeric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM50625712(CHEMBL5407888)
Affinity DataKi:  6.18E+3nMAssay Description:Binding affinity to pancreatic lipase (unknown origin) assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM50618926(CHEMBL5413231)
Affinity DataIC50: 6.27E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50618911(CHEMBL5405185)
Affinity DataIC50: 6.75E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50367213(CHEMBL4175223)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50367216(CHEMBL4176621)
Affinity DataIC50: 7.38E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50367135(CHEMBL4160094)
Affinity DataIC50: 7.82E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50232348(CHEMBL4077903)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human pancreatic lipase using 4-methylumbelliferyl oleate as substrate after 30 mins by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50625712(CHEMBL5407888)
Affinity DataIC50: 9.01E+3nMAssay Description:Inhibition of pancreatic lipase (unknown origin) by spectrophotometeric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
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