Affinity DataKi: 0.00105nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.00260nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.00300nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the absence of NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.00400nMAssay Description:50% Inhibition of stereospecific [3H]-naltrexone (10e-9 M) binding towards opiate receptor in rat brain homogenateMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.00400nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the presence of NaClMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00500nMAssay Description:Binding affinity against rat Opioid receptor delta 1 expressed in CHO cells determined by competitive inhibition of 1 nM [3H]DPDPE.More data for this Ligand-Target Pair
Affinity DataKi: 0.00720nMAssay Description:Tested for binding activity against delta1 opioid receptor using [3H]DPDPE ligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.00900nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the absence of NaClMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Binding affinity against rat Opioid receptor delta 1 expressed in CHO cells determined by competitive inhibition of 1 nM [3H]DPDPE.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Inhibitory activity against forskolin-stimulated cAMP production in chinese hamster ovary cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Compound was evaluated for binding affinity against delta opioid receptor of rat forebrain using [3H]-DPDPE as the radioligand using competition bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.0130nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the absence of NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.0150nMAssay Description:The compound was tested for binding affinity against opioid receptor in rat brain membranes, using [3H]dihydromorphine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.0180nMAssay Description:The binding affinity was measured using [3H]- TIPPsi against Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.0187nMAssay Description:Agonistic activity for opioid receptor deltaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0190nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the absence of NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0210nMAssay Description:Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0210nMAssay Description:Displacement of [3H]deltorphin II from rat delta opioid receptor in brain P2 synaptosomesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.0270nMAssay Description:50% Inhibition of stereospecific [3H]-naltrexone (10e-9 M) binding towards opiate receptor in rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0280nMAssay Description:The binding affinity was measured using [3H]- TIPPsi against Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:The binding affinity was measured using [3H]-DIDII against Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.0310nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0310nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in Sprague-Dawley rat brain synaptosomal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0310nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 in rat brain synaptosomes using [3H]deltorphin II as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.0310nMAssay Description:Binding affinity at Opioid receptor delta 1 using rat brain receptor (P2 synaptosome) assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Binding affinity at Opioid receptor delta 1 using rat brain receptor (P2 synaptosome) assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:The binding affinity was measured using [3H]-DIDII against Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain synaptosomes P2 fractionMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Binding affinity to delta opioid receptor in Sprague-Dawley rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Displacement of [3H]deltorphin II from rat delta opioid receptor in brain P2 synaptosomesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0360nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of [3H]-DADLE binding to rat brain delta receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Binding affinity at Opioid receptor delta 1 from rat brain synaptosomal preparations by H-Dmt-Tic-OH displacement.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Binding affinity against rat Opioid receptor delta 1 expressed in CHO cells determined by competitive inhibition of 1 nM [3H]DPDPE.More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Compound was evaluated for its ability to displace [3H]p-CI-DPDPE in C6 glioma cells expressing the cloned Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Binding affinity at Opioid receptor delta 1 using rat brain receptor (P2 synaptosome) assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0450nMAssay Description:Displacement of [3H]DPDPE (0.63 nM) from Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 0.0470nMAssay Description:Tested for binding activity against delta opioid receptor using [3H]naltridole ligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.0470nMAssay Description:The binding affinity was measured using [3H]naltrindole against Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.0470nMAssay Description:Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomesMore data for this Ligand-Target Pair





3D Structure (crystal)






























