Compile Data Set for Download or QSAR
Report error Found 1031 for UniProtKB: P62942
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23334BDBM23334(3-(pyridin-3-yl)propyl (2S)-1-(3,3-dimethyl-2-oxop...)
Affinity DataKi:  0.0100nMAssay Description:Ability to inhibit peptidyl-prolyl isomerase (PPIase, or rotamase) activity of FK506 binding protein 12More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651709BDBM50651709(CHEMBL5634031)
Affinity DataKd:  0.0300nMAssay Description:Binding affinity to human FKBP12 expressed in Escherichia coli BL21 DE3 Gold assessed as dissociation constant incubated for 30 mins by competitive f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 36609BDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)
Affinity DataKd:  0.130nMAssay Description:Binding affinity to human FKBP12 expressed in Escherichia coli BL21 DE3 Gold assessed as dissociation constant incubated for 30 mins by competitive f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 36609BDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to FKBP12 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030448BDBM50030448(CHEMBL269732 | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN ...)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to human FKBP12 expressed in Escherichia coli BL21 DE3 Gold assessed as dissociation constant incubated for 30 mins by competitive f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030448BDBM50030448(CHEMBL269732 | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN ...)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to FK506 binding protein 12 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030448BDBM50030448(CHEMBL269732 | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN ...)
Affinity DataKd:  0.200nMAssay Description:The compound was evaluated for its affinity to the binding domain of immunophilin FK506 binding protein 12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 36609BDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)
Affinity DataKi:  0.200nMAssay Description:Compound was tested for its ability to inhibit FK506 binding protein 12 rotamase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 514000BDBM514000((S)-1-(2-((2R,3R,6S)-6-((2R,3R,4S,6E,9E,11R,12R)-1...)
Affinity DataKd:  0.210nMAssay Description:The binding of compounds of the invention to FKBP12 can be determined using the following protocol.General ProtocolThis protocol utilizes Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609430BDBM50609430(CHEMBL5275279)
Affinity DataEC50:  0.270nMAssay Description:Induction of degradation of FKBP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597684BDBM597684(US11603377, Compound 5)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 36609BDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597683BDBM597683(US11603377, Compound 4)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597715BDBM597715(US11603377, Compound 36)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597686BDBM597686(US11603377, Compound 7)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597685BDBM597685(US11603377, Compound 6)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597688BDBM597688(US11603377, Compound 9)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597687BDBM597687(US11603377, Compound 8)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597708BDBM597708(US11603377, Compound 35 | US11603377, Compound 29)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597707BDBM597707(US11603377, Compound 34 | US11603377, Compound 28)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597740BDBM597740(US11603377, Compound 61)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597710BDBM597710(US11603377, Compound 31)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597709BDBM597709(US11603377, Compound 30)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597712BDBM597712(US11603377, Compound 33)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597711BDBM597711(US11603377, Compound 32)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597744BDBM597744(US11603377, Compound 65)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597708BDBM597708(US11603377, Compound 35 | US11603377, Compound 29)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597747BDBM597747(US11603377, Compound 68)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597681BDBM597681(US11603377, Compound 2)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597707BDBM597707(US11603377, Compound 34 | US11603377, Compound 28)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597746BDBM597746(US11603377, Compound 67)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597700BDBM597700(US11603377, Compound 21)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597699BDBM597699(US11603377, Compound 20)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597702BDBM597702(US11603377, Compound 23)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597734BDBM597734(US11603377, Compound 55)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597701BDBM597701(US11603377, Compound 22)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597704BDBM597704(US11603377, Compound 25)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597703BDBM597703(US11603377, Compound 24)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597735BDBM597735(US11603377, Compound 56)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597706BDBM597706(US11603377, Compound 27)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597705BDBM597705(US11603377, Compound 26)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597738BDBM597738(US11603377, Compound 59)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517882BDBM50517882(CHEMBL4449096)
Affinity DataKi:  0.300nMAssay Description:Inhibition of His6 tagged human FKBP12 expressed in Escherichia coli BL21(DE3) cells using succinylALPF-p-nitroanilide as substrate by fluorescence p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597692BDBM597692(US11603377, Compound 16 | US11603377, Compound 13)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597694BDBM597694(US11603377, Compound 15)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597696BDBM597696(US11603377, Compound 17)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597728BDBM597728(US11603377, Compound 49)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597692BDBM597692(US11603377, Compound 16 | US11603377, Compound 13)
Affinity DataKd: <0.300nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 696416BDBM696416(C16-(1,1-dioxido-1,2-thiazetidin-2-yl)-C32-deoxo-r...)
Affinity DataKd:  0.320nMAssay Description:N-terminal avi-his6 tagged FKBP fusions to FKBP12, FKBP51 and FKBP52 were expressed in E. coli and purified using standard chromatography. Each prote...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 696416BDBM696416(C16-(1,1-dioxido-1,2-thiazetidin-2-yl)-C32-deoxo-r...)
Affinity DataKd:  0.320nMAssay Description:N-terminal avi-his6 tagged FKBP fusions to FKBP12, FKBP51 and FKBP52 were expressed in E. coli and purified using standard chromatography. Each prote...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/13/2025
Entry Details
US Patent

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