Compile Data Set for Download or QSAR
Report error Found 9 of affinity data for UniProtKB/TrEMBL: P70172
TargetIleal sodium/bile acid cotransporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM159808(US9040518, 25 | BDBM50434850)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50434849(CHEMBL2385105 | US9040518, 6)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50434846(CHEMBL2387399 | US9040518, 35)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM47370(BDBM50434858 | US9040518, 26)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50134411((7R,9R)-7-Butyl-7-ethyl-2,3-dimethoxy-9-phenyl-6,7...)
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50459099(CHEMBL4202981)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of mouse IBAT expressed in COS cells assessed as reduction in [3H]taurocholic acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50459098(CHEMBL4205214)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of mouse IBAT expressed in COS cells assessed as reduction in [3H]taurocholic acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50459096(CHEMBL4217797)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of mouse IBAT expressed in COS cells assessed as reduction in [3H]taurocholic acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50390996(CHEMBL2074988)
Affinity DataKi:  68nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate accumulation in ASBT-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed