Compile Data Set for Download or QSAR
Report error Found 29 of affinity data for UniProtKB/TrEMBL: Q06518
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50386178BDBM50386178(ONO-1714 | CHEMBL1800346)
Affinity DataKi:  1.80nMAssay Description:Inhibition of rat iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462408BDBM50462408(CHEMBL4245460)
Affinity DataIC50: 900nMAssay Description:Inhibition of rat iNOS after 12 to 24 hrs in presence of [gamma32P]ATP by electrophoretic mobility shift assaysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072297BDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataIC50: 2.20E+3nMAssay Description:Tested for inhibition of rat brain inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365330BDBM50365330(CHEMBL1956107)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of rat recombinant iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]L-arginine to [3H]L-citrulline in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438535BDBM50438535(CHEMBL2414836)
Affinity DataIC50: 9.81E+3nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438534BDBM50438534(CHEMBL2414846)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438533BDBM50438533(CHEMBL2414845)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030279BDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataIC50: 1.80E+4nMAssay Description:Tested for inhibition of rat brain inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206065BDBM50206065(N-{2-[1-(3-methoxy-benzyl)-piperidin-4-ylamino]-be...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of rat inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225106BDBM50225106(NG-nitroarginine | 2-Amino-5-(N'-nitro-guanidino)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Tested for inhibition of rat brain inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438532BDBM50438532(CHEMBL2414844)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206073BDBM50206073(N-[2-(2-pyridin-2-yl-ethylamino)-benzothiazol-6-yl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206066BDBM50206066(N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl]-piperidin-4-y...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of rat inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099401BDBM50099401(1-(2-Trifluoromethyl-phenyl)-1H-imidazole | CHEMBL...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of rat iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438531BDBM50438531(CHEMBL2414855)
Affinity DataIC50: 2.99E+4nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206064BDBM50206064(N-[2-(1-benzyl-piperidin-4-ylamino)-benzothiazol-6...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of rat inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438530BDBM50438530(CHEMBL2414851)
Affinity DataIC50: 4.02E+4nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206070BDBM50206070(N-[2-(2-morpholin-4-yl-ethylamino)-benzothiazol-6-...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of rat inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438529BDBM50438529(CHEMBL2414840)
Affinity DataIC50: 5.32E+4nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438528BDBM50438528(CHEMBL2414843)
Affinity DataIC50: 5.76E+4nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438527BDBM50438527(CHEMBL2414838)
Affinity DataIC50: 6.03E+4nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438526BDBM50438526(CHEMBL2414841)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438525BDBM50438525(CHEMBL2414847)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063300BDBM50063300(l-NIL | CHEMBL1744034 | (L-N6-1-iminoethyl)lysine ...)
Affinity DataIC50: 9.20E+4nMAssay Description:Tested for inhibition of rat brain inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379737BDBM50379737(CHEMBL2011128)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438524BDBM50438524(CHEMBL2414852)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50207159BDBM50207159(hydrazinecarboximidamide | 2-aminoguanidine | 2-az...)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of iNOS-mediated NO production in IL-1beta/IFNgamma-stimulated rat RINmF cells by Griess reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030276BDBM50030276(7-Acetimidoylamino-2-amino-heptanoic acid | CHEMBL...)
Affinity DataIC50: 8.08E+5nMAssay Description:Tested for inhibition of rat brain inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030277BDBM50030277((R)-6-Acetimidoylamino-2-amino-hexanoic acid | CHE...)
Affinity DataIC50: 2.80E+6nMAssay Description:Tested for inhibition of rat brain inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed