Compile Data Set for Download or QSAR
Report error Found 42 for UniProtKB: Q8R493
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270397BDBM50270397(CHEMBL4070098)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270370BDBM50270370(CHEMBL4101688)
Affinity DataIC50: 520nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270396BDBM50270396(CHEMBL4073773)
Affinity DataIC50: 600nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270401BDBM50270401(CHEMBL4064521)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270364BDBM50270364(CHEMBL4064684)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270402BDBM50270402(CHEMBL4097677)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270368BDBM50270368(CHEMBL4082570)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006634BDBM50006634(CHEMBL3235510)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006638BDBM50006638(CHEMBL2140445)
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270372BDBM50270372(CHEMBL4104998)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006640BDBM50006640(CHEMBL593001)
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270371BDBM50270371(CHEMBL4087153)
Affinity DataIC50: 5.70E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270375BDBM50270375(CHEMBL4075463)
Affinity DataIC50: 6.20E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270388BDBM50270388(CHEMBL4083525)
Affinity DataIC50: 7.20E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270382BDBM50270382(CHEMBL4082090)
Affinity DataIC50: 7.20E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270405BDBM50270405(CHEMBL4102579)
Affinity DataIC50: 9.10E+3nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270407BDBM50270407(CHEMBL1570477)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270395BDBM50270395(CHEMBL4092845)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014648BDBM50014648(CHEMBL555787 | 6,7-Dimethoxy-2-methyl-1,2,3,4-tetr...)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270399BDBM50270399(CHEMBL4073109)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270373BDBM50270373(CHEMBL4073899)
Affinity DataIC50: 1.50E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270362BDBM50270362(CHEMBL4077320)
Affinity DataIC50: 1.60E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270389BDBM50270389(CHEMBL4061335)
Affinity DataIC50: 2.30E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270390BDBM50270390(CHEMBL4062419)
Affinity DataIC50: 2.40E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006633BDBM50006633(CHEMBL3235509)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270369BDBM50270369(CHEMBL4083684)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270403BDBM50270403(CHEMBL4080088)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270374BDBM50270374(CHEMBL4099972)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270367BDBM50270367(CHEMBL4067385)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270365BDBM50270365(CHEMBL4078302)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270406BDBM50270406(CHEMBL4084130)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270394BDBM50270394(CHEMBL4061094)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270393BDBM50270393(CHEMBL4071054)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006628BDBM50006628(CHEMBL3235504)
Affinity DataIC50: 3.10E+4nMAssay Description:Antagonist activity at mouse alpha4/beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced activity by FLIPR membrane p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270366BDBM50270366(CHEMBL4087050)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270398BDBM50270398(CHEMBL4067398)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270361BDBM50270361(CHEMBL4077524)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270363BDBM50270363(CHEMBL4086188)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270376BDBM50270376(Laudanosine)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270404BDBM50270404(CHEMBL4097292)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270400BDBM50270400(CHEMBL363360)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270377BDBM50270377(CHEMBL4081330)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed