Compile Data Set for Download or QSAR
Report error Found 542 for UniProtKB: Q9Y478
LigandPNGBDBM563544(US11407768, Compound 1)
Affinity DataEC50:  0.0500nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563546(US11407768, Compound 3)
Affinity DataEC50:  0.0900nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563547(US11407768, Compound 4)
Affinity DataEC50:  0.100nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565695(US11407768, Compound 74)
Affinity DataEC50:  0.150nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565454(US11407768, Compound 53)
Affinity DataEC50:  0.230nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565696(US11407768, Compound 75)
Affinity DataEC50:  0.370nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563553(US11407768, Compound 10)
Affinity DataEC50:  0.400nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563495(US11407763, Example 45 | (2S)-2-amino-3-(4-(2- am...)
Affinity DataEC50:  0.460nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563556(US11407768, Compound 14)
Affinity DataEC50:  0.5nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM237992(US9394285, 75)
Affinity DataEC50:  0.5nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM563558(US11407768, Compound 29)
Affinity DataEC50:  0.560nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565456(US11407768, Compound 54)
Affinity DataEC50:  0.570nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563549(US11407768, Compound 6)
Affinity DataEC50:  0.620nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565561(US11407768, Compound 71)
Affinity DataEC50:  0.630nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563501(US11407768, Compound 22)
Affinity DataEC50:  0.630nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563503(US11407768, Compound 30 | (2S)-2-amino-3-(4-(2- am...)
Affinity DataEC50:  0.650nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM50195477(CHEMBL3979403)
Affinity DataEC50:  0.700nMAssay Description:Activation of recombinant human His-tagged AMPK alpha2 (2 to 552 residues)/beta1 (2 to 270 residues)/gamma2 (2 to 569 residues) expressed in baculovi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM565449(US11407768, Compound 51)
Affinity DataEC50:  0.720nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563504(US11407768, Compound 32)
Affinity DataEC50:  0.760nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565498(US11407768, Compound 65)
Affinity DataEC50:  0.770nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565503(US11407768, Compound 66)
Affinity DataEC50:  0.800nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565452(US11407768, Compound 52)
Affinity DataEC50:  0.810nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563563(US11407768, Compound 36)
Affinity DataEC50:  0.840nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563560(US11407768, Compound 31)
Affinity DataEC50:  0.850nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565483(US11407768, Compound 60)
Affinity DataEC50:  0.850nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565483(US11407768, Compound 60)
Affinity DataEC50:  0.850nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563548(US11407768, Compound 5)
Affinity DataEC50:  0.860nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565476(US11407768, Compound 57)
Affinity DataEC50:  0.890nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565506(US11407768, Compound 67)
Affinity DataEC50:  0.930nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565474(US11407768, Compound 56)
Affinity DataEC50:  0.930nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565478(US11407768, Compound 58)
Affinity DataEC50:  0.930nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563562(US11407768, Compound 33)
Affinity DataEC50:  0.960nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM213202(US9290517, 133)
Affinity DataEC50:  1nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
US Patent

LigandPNGBDBM213199(US9290517, 129)
Affinity DataEC50:  1nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
US Patent

LigandPNGBDBM50195478(CHEMBL3959081)
Affinity DataEC50:  1nMAssay Description:Activation of full length human recombinant AMPK alpha1/beta1/gamma1 expressed in baculovirus infected sf21 cells using 5'-FAM-SAMS peptide substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM213209(US9290517, 150)
Affinity DataEC50:  1nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
US Patent

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
LigandPNGBDBM565481(US11407768, Compound 59)
Affinity DataEC50:  1.04nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563566(US11407768, Compound 40)
Affinity DataEC50:  1.08nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565494(US11407768, Compound 63)
Affinity DataEC50:  1.09nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563568(US11407768, Compound 48)
Affinity DataEC50:  1.16nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM50195538(CHEMBL3898977)
Affinity DataEC50:  1.20nMAssay Description:Activation of full length human recombinant AMPK alpha1/beta1/gamma1 expressed in baculovirus infected sf21 cells using SAMS peptide substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM563550(US11407768, Compound 7)
Affinity DataEC50:  1.22nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM237984(US9394285, 67)
Affinity DataEC50:  1.30nMAssay Description:Activation of recombinant human AMPK alpha1/beta1/gamma1 using Cy5-labelled SAMS as substrate assessed as protection from Thr172 residue dephosphoryl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMed
LigandPNGBDBM565492(US11407768, Compound 62)
Affinity DataEC50:  1.30nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565694(US11407768, Compound 73)
Affinity DataEC50:  1.33nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565486(US11407768, Compound 61)
Affinity DataEC50:  1.36nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565693(US11407768, Compound 72)
Affinity DataEC50:  1.38nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM563545(US11407768, Compound 2)
Affinity DataEC50:  1.40nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

LigandPNGBDBM565496(US11407768, Compound 64)
Affinity DataEC50:  1.40nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
US Patent

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