Compile Data Set for Download or QSAR
Report error Found 324 of affinity data for UniProtKB/TrEMBL: Q9Z2A7
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209531BDBM209531(US9271969, 19)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209530BDBM209530(US9271969, 18)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209526BDBM209526(US9271969, 14)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209544BDBM209544(US9271969, 32)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209551BDBM209551(US9271969, 39)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209550BDBM209550(US9271969, 38)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437388BDBM50437388(CHEMBL3037924)
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50385398BDBM50385398(CHEMBL2036730)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209532BDBM209532(US9271969, 20)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50009445BDBM50009445(CHEMBL3233889)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523583BDBM50523583(CHEMBL4585408)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523584BDBM50523584(CHEMBL4452940)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523609BDBM50523609(CHEMBL4531443)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523594BDBM50523594(CHEMBL4453443)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523628BDBM50523628(CHEMBL4557603)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50117151BDBM50117151(CHEMBL3613351)
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437393BDBM50437393(CHEMBL2408630)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523604BDBM50523604(CHEMBL4458847)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523586BDBM50523586(CHEMBL4543944)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437391BDBM50437391(CHEMBL2408632)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437389BDBM50437389(CHEMBL3037925)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523588BDBM50523588(CHEMBL4483357)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437374BDBM50437374(CHEMBL2408470)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437387BDBM50437387(CHEMBL2408472)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437391BDBM50437391(CHEMBL2408632)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437390BDBM50437390(CHEMBL2408633)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437386BDBM50437386(CHEMBL2408620)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50505237BDBM50505237(CHEMBL4591140)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523601BDBM50523601(CHEMBL4467163)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437392BDBM50437392(CHEMBL2408631)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523580BDBM50523580(CHEMBL4572398)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437383BDBM50437383(CHEMBL2408623)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50117187BDBM50117187(CHEMBL3613341)
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523587BDBM50523587(CHEMBL4460750)
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50117150BDBM50117150(CHEMBL3613355)
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50117149BDBM50117149(CHEMBL3613349)
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523605BDBM50523605(CHEMBL4443023)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209537BDBM209537(US9271969, 25)
Affinity DataIC50: 5.30nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50523619BDBM50523619(CHEMBL4592144)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437390BDBM50437390(CHEMBL2408633)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209534BDBM209534(US9271969, 22)
Affinity DataIC50: 7.60nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50031502BDBM50031502(CHEMBL3342774)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50117189BDBM50117189(CHEMBL3613340)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50502593BDBM50502593(CHEMBL4578901)
Affinity DataEC50:  8nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50009439BDBM50009439(CHEMBL3233885)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50502595BDBM50502595(CHEMBL4554065)
Affinity DataEC50:  8nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50394726BDBM50394726(CHEMBL2165819)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse DGAT1 using [1-14C]decanoyl-CoA substrate by phospholipid flash plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50031502BDBM50031502(CHEMBL3342774)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50117184BDBM50117184(CHEMBL3613347)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50437373BDBM50437373(CHEMBL2408471)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
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