Compile Data Set for Download or QSAR
Report error Found 16 of affinity data for UniProtKB/TrEMBL: E2JF22
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636536BDBM50636536(CHEMBL5559782)
Affinity DataEC50:  150nMAssay Description:Agonist activity at mouse PIEZO1 transfected in HEK293-T-REx cells assessed as activation of intracellular Ca2+ levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636536BDBM50636536(CHEMBL5559782)
Affinity DataEC50:  150nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636537BDBM50636537(CHEMBL5560055)
Affinity DataEC50:  280nMAssay Description:Agonist activity at mouse PIEZO1 transfected in HEK293-T-REx cells assessed as activation of intracellular Ca2+ levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600401BDBM50600401(CHEMBL4303374)
Affinity DataEC50:  600nMAssay Description:Agonist activity at mouse PIEZO1 transfected in HEK293-T-REx cells assessed as activation of intracellular Ca2+ levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600401BDBM50600401(CHEMBL4303374)
Affinity DataEC50:  2.21E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653266BDBM50653266(CHEMBL6142234)
Affinity DataEC50:  1.29E+4nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600401BDBM50600401(CHEMBL4303374)
Affinity DataEC50:  1.71E+4nMAssay Description:Agonist activity at mouse Piezo1 transfected in human HEK293T cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653268BDBM50653268(CHEMBL6151272)
Affinity DataEC50:  4.42E+4nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600401BDBM50600401(CHEMBL4303374)
Affinity DataKd:  4.56E+4nMAssay Description:Binding affinity to CM5 sensor chip-immobilized mouse Piezo1 (1 to 2190 residues) assessed as dissociation constant by real-time SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653267BDBM50653267(CHEMBL6102148)
Affinity DataEC50: >1.50E+5nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600403BDBM50600403(CHEMBL5181053)
Affinity DataEC50:  1.58E+5nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600403BDBM50600403(CHEMBL5181053)
Affinity DataEC50:  1.58E+5nMAssay Description:Inhibition of mouse Piezo1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600402BDBM50600402(CHEMBL5208985)
Affinity DataEC50:  2.00E+5nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600402BDBM50600402(CHEMBL5208985)
Affinity DataEC50:  2.00E+5nMAssay Description:Inhibition of mouse Piezo1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600403BDBM50600403(CHEMBL5181053)
Affinity DataKd:  2.24E+6nMAssay Description:Binding affinity to mouse Piezo1 assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600402BDBM50600402(CHEMBL5208985)
Affinity DataKd:  2.75E+6nMAssay Description:Binding affinity to mouse Piezo1 assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed