Compile Data Set for Download or QSAR
Report error Found 318 of affinity data for UniProtKB/TrEMBL: O43193
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM85389(CAS_52906-92-0 | Motilin)
Affinity DataEC50:  0.0398nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143028(8'N-[1-[1-carbamoyl-3-phenyl-(1S)-propylcarbamoyl]...)
Affinity DataEC50:  0.0470nMAssay Description:In vitro effective concentration towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143037(CHEMBL411576 | MOTILIN)
Affinity DataEC50:  0.150nMAssay Description:In vitro effective concentration towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143038(8'N-[1-[1-carbamoyl-3-phenyl-(1S)-propylcarbamoyl]...)
Affinity DataEC50:  0.220nMAssay Description:In vitro effective concentration towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143032(8'N-[1-(1-carbamoyl-3-phenylpropylcarbamoyl)-3-phe...)
Affinity DataEC50:  0.350nMAssay Description:In vitro effective concentration towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002694(MOTILIN)
Affinity DataKi:  0.360nMAssay Description:Displacement of [125I]motilin from human MOTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143028(8'N-[1-[1-carbamoyl-3-phenyl-(1S)-propylcarbamoyl]...)
Affinity DataKi:  0.700nMAssay Description:In vitro binding affinity towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599720(H-Motilin | CHEMBL525634)
Affinity DataEC50:  0.970nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143032(8'N-[1-(1-carbamoyl-3-phenylpropylcarbamoyl)-3-phe...)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599738(CHEMBL5192530)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599734(CHEMBL5179573)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50214268((5R,8R,11S)-8-(propan-2-yl)-11-(pyrrolidin-1-ylmet...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143038(8'N-[1-[1-carbamoyl-3-phenyl-(1S)-propylcarbamoyl]...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412537(CHEMBL465917)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599726(CHEMBL5179543)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599725(CHEMBL5187928)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311412(N-(3-((1H-pyrazol-3-yl)methyl)-2,3,4,5-tetrahydro-...)
Affinity DataEC50:  2.51nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412526(CHEMBL518618)
Affinity DataEC50:  2.51nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599735(CHEMBL5192584)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143039(8'N-[1-[1-carbamoyl-3-phenyl-(1R)-propylcarbamoyl]...)
Affinity DataKi:  2.70nMAssay Description:In vitro binding affinity towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50214266((5R,8R,11S)-11-[(methylamino)methyl]-8-(propan-2-y...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143037(CHEMBL411576 | MOTILIN)
Affinity DataKi:  3.10nMAssay Description:In vitro binding affinity towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412523(CHEMBL465271)
Affinity DataEC50:  3.16nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415674(CHEMBL1079186)
Affinity DataEC50:  3.16nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421366(CHEMBL353526)
Affinity DataIC50: 3.20nMAssay Description:Compound was tested for in vitro motilin receptor binding affinityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50344952((2R,3S,4R,5R,8R,9S,10S,11R,12S)-5-ethyl-11-((2S,3R...)
Affinity DataKi:  3.40nMAssay Description:In vitro binding affinity towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM85846(Erythromycin-A enol ether | EM523 | CAS_33396-29-1...)
Affinity DataIC50: 3.40nMAssay Description:Compound was tested for in vitro motilin receptor binding affinityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412539(CHEMBL518229)
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50292985(3-((1-[(4-([(3S)-3-Methyl-1-piperazinyl]methyl)phe...)
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311416(N-(3-((1H-pyrazol-3-yl)methyl)-2,3,4,5-tetrahydro-...)
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50344952((2R,3S,4R,5R,8R,9S,10S,11R,12S)-5-ethyl-11-((2S,3R...)
Affinity DataEC50:  4.20nMAssay Description:In vitro effective concentration towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599737(CHEMBL5171964)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599729(CHEMBL5184722)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50214268((5R,8R,11S)-8-(propan-2-yl)-11-(pyrrolidin-1-ylmet...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599736(CHEMBL5196982)
Affinity DataEC50:  4.70nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421369(CHEMBL262052)
Affinity DataIC50: 4.70nMAssay Description:Compound was tested for in vitro motilin receptor binding affinityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311415(N-(3-((1H-pyrazol-3-yl)methyl)-2,3,4,5-tetrahydro-...)
Affinity DataEC50:  5.01nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311423(7-((6-(4-fluorophenyl)pyridin-3-ylsulfonyl)methyl)...)
Affinity DataEC50:  5.01nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254970([4'-((3R,5S)-3,5-Dimethyl-piperazin-1-ylmethyl)-bi...)
Affinity DataEC50:  5.01nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412541(CHEMBL465095)
Affinity DataEC50:  5.01nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599731(CHEMBL5201797)
Affinity DataEC50:  5.30nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50599733(CHEMBL5203126)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at human GPR38 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50214266((5R,8R,11S)-11-[(methylamino)methyl]-8-(propan-2-y...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50214270(1-{[(5R,8R,11S)-5-[(4-chlorophenyl)methyl]-6,9,12-...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50214264(1-{[(5R,8R,11S)-6,9,12-trioxo-8-(propan-2-yl)-5-{[...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412531(CHEMBL463881)
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311413(N-(3-((1H-pyrazol-3-yl)methyl)-2,3,4,5-tetrahydro-...)
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421367(CHEMBL351216)
Affinity DataIC50: 6.90nMAssay Description:Compound was tested for in vitro motilin receptor binding affinityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143039(8'N-[1-[1-carbamoyl-3-phenyl-(1R)-propylcarbamoyl]...)
Affinity DataEC50:  7.30nMAssay Description:In vitro effective concentration towards human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
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