Compile Data Set for Download or QSAR
Report error Found 210 of affinity data for UniProtKB/TrEMBL: P00375
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50023681BDBM50023681(2-{4-[(2,4-Diamino-5,7-dimethyl-pyrido[2,3-d]pyrim...)
Affinity DataKi:  0.00200nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010932BDBM50010932(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoyl...)
Affinity DataKi:  0.00210nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016323BDBM50016323(CHEMBL12094 | 2-{4-[(2,4-Diamino-5-methyl-pyrido[2...)
Affinity DataKi:  0.00212nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367055BDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...)
Affinity DataKi:  0.00230nMAssay Description:Tested for inhibition of dihydrofolate reductase enzyme from mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025009BDBM50025009(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoyl...)
Affinity DataKi:  0.00240nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028641BDBM50028641(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-1,1-dimethyl-e...)
Affinity DataKi:  0.00260nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016324BDBM50016324(CHEMBL11610 | 2-{4-[(2,4-Diamino-5-methyl-pyrido[2...)
Affinity DataKi:  0.00264nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028533BDBM50028533(4-Carbamoyl-2-{4-[(2,4-diamino-pteridin-6-ylmethyl...)
Affinity DataKi:  0.00270nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028539BDBM50028539(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  0.00270nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016460BDBM50016460(Edatrexate | GNF-Pf-63 | (S)-2-{4-[1-(2,4-Diamino-...)
Affinity DataKi:  0.00280nMAssay Description:Concentration inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028542BDBM50028542(derivative of methotrexate | CHEMBL293546)
Affinity DataKi:  0.00280nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004544BDBM50004544(2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-propyl]-...)
Affinity DataKi:  0.00280nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028536BDBM50028536(4-(Carboxymethyl-carbamoyl)-2-{4-[(2,4-diamino-pte...)
Affinity DataKi:  0.00290nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016326BDBM50016326(CHEMBL428862 | 2-{4-[(2,4-Diamino-5-methyl-pyrido[...)
Affinity DataKi:  0.00293nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50405400BDBM50405400(CHEMBL2051987)
Affinity DataKi:  0.00300nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028605BDBM50028605(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-propyl-ami...)
Affinity DataKi:  0.00300nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50405400BDBM50405400(CHEMBL2051987)
Affinity DataKi:  0.00300nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18050BDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  0.00320nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010932BDBM50010932(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoyl...)
Affinity DataKi:  0.00340nMAssay Description:Concentration inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028541BDBM50028541(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  0.00350nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367055BDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...)
Affinity DataKi:  0.00355nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028531BDBM50028531(4-Benzylcarbamoyl-2-{4-[(2,4-diamino-pteridin-6-yl...)
Affinity DataKi:  0.00360nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016325BDBM50016325(CHEMBL275309 | 2-{4-[(2,4-Diamino-pyrido[2,3-d]pyr...)
Affinity DataKi:  0.00365nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043393BDBM50043393(2-({4-[(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmet...)
Affinity DataKi:  0.00365nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028538BDBM50028538(derivative of methotrexate | CHEMBL293147)
Affinity DataKi:  0.00370nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028540BDBM50028540(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  0.00390nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50023682BDBM50023682(2-{4-[(2,4-Diamino-5-methyl-7-phenyl-pyrido[2,3-d]...)
Affinity DataKi: >0.00400nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50023684BDBM50023684(2-{4-[(2,4-Diamino-7-methyl-5-phenyl-pyrido[2,3-d]...)
Affinity DataKi: >0.00400nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50023680BDBM50023680(2-{4-[(2,4-Diamino-7-phenyl-pyrido[2,3-d]pyrimidin...)
Affinity DataKi: >0.00400nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010932BDBM50010932(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoyl...)
Affinity DataKi:  0.00400nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226274BDBM50226274(CHEMBL3349020)
Affinity DataKi:  0.00400nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18050BDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  0.00400nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367055BDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...)
Affinity DataKi:  0.00400nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025009BDBM50025009(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoyl...)
Affinity DataKi:  0.00400nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50023683BDBM50023683(2-{4-[(2,4-Diamino-7-methyl-pyrido[2,3-d]pyrimidin...)
Affinity DataKi: >0.00400nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026389BDBM50026389(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  0.00400nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18050BDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  0.00430nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043396BDBM50043396(2-({4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-na...)
Affinity DataKi:  0.00455nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043399BDBM50043399(2-({4-[(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmet...)
Affinity DataKi:  0.00465nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026392BDBM50026392(2-[3-(2-Carboxy-2-{4-[(2,4-diamino-pteridin-6-ylme...)
Affinity DataKi:  0.00471nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18050BDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  0.00480nMAssay Description:In vitro inhibition of dihydrofolate reductase (DHFR) in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18050BDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  0.00482nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043395BDBM50043395(2-({4-[(2,4-Diamino-5-methyl-pyrido[2,3-d]pyrimidi...)
Affinity DataKi:  0.00484nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026399BDBM50026399(3-(4-Chloro-benzoylamino)-2-{4-[(2,4-diamino-pteri...)
Affinity DataKi:  0.00498nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016460BDBM50016460(Edatrexate | GNF-Pf-63 | (S)-2-{4-[1-(2,4-Diamino-...)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043400BDBM50043400(2-({4-[(2,4-Diamino-5-methyl-pyrido[2,3-d]pyrimidi...)
Affinity DataKi:  0.00508nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043398BDBM50043398(2-({4-[(2,4-Diamino-quinazolin-6-ylmethyl)-amino]-...)
Affinity DataKi:  0.00520nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014707BDBM50014707(CHEMBL431359 | 2-{4-[2-(2,4-Diamino-pteridin-6-yl)...)
Affinity DataKi:  0.00520nMAssay Description:Concentration inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043394BDBM50043394(2-({4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-am...)
Affinity DataKi:  0.00522nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Cornell University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18050BDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  0.00528nMAssay Description:The compound was tested for its inhibitory activity against dihydrofolate reductase(DHFR) derived from L1210 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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