Compile Data Set for Download or QSAR
Report error Found 15224 for UniProtKB: P00918
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11929(2-N-[(4-methylphenyl)methyl]thiophene-2,5-disulfon...)
Affinity DataKd:  0.460nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11930(2-N-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfo...)
Affinity DataKd:  0.490nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11931(2-N-(thiophen-2-ylmethyl)thiophene-2,5-disulfonami...)
Affinity DataKd:  0.830nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11932(4-hydroxy-1,1-dioxo-2-(thiophen-2-ylmethyl)-2H,3H,...)
Affinity DataKd:  0.200nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11933(4-hydroxy-2-(4-methoxyphenyl)-1,1-dioxo-2H,3H,4H-1...)
Affinity DataKd:  0.160nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11934((4R)-4-(ethylamino)-2-(2-methoxyethyl)-1,1-dioxo-2...)
Affinity DataKd:  0.320nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataKd:  0.130nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11935(2-(3-methoxyphenyl)-1,1-dioxo-2H,3H,4H-1,7,2-thien...)
Affinity DataKd:  0.100nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11936((4R)-2-(3-methoxyphenyl)-4-(methylamino)-1,1-dioxo...)
Affinity DataKd:  0.100nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11937((4S)-2-(3-methoxyphenyl)-4-(methylamino)-1,1-dioxo...)
Affinity DataKd:  1.70nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11938(2-(3-methoxyphenyl)-1,1-dioxo-2H-1,7,2-thieno[3,2-...)
Affinity DataKd:  0.130nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12013(CHEMBL302715 | N-benzyl-4-sulfamoylbenzamide | 4-(...)
Affinity DataKd:  5.60nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12014(N-[(2-fluorophenyl)methyl]-4-sulfamoylbenzamide | ...)
Affinity DataKd:  2.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12015(N-[(4-fluorophenyl)methyl]-4-sulfamoylbenzamide | ...)
Affinity DataKd:  3.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12016(N-[(2,3-difluorophenyl)methyl]-4-sulfamoylbenzamid...)
Affinity DataKd:  1.60nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12017(N-[(2,4-difluorophenyl)methyl]-4-sulfamoylbenzamid...)
Affinity DataKd:  3.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12018(N-[(2,5-difluorophenyl)methyl]-4-sulfamoylbenzamid...)
Affinity DataKd:  2.20nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12019(N-[(2,6-difluorophenyl)methyl]-4-sulfamoylbenzamid...)
Affinity DataKd:  3.90nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12020(CHEMBL66907 | 4-(AMINOSULFONYL)-N-[(2,3,4-TRIFLUOR...)
Affinity DataKd:  3.80nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12021(4-(AMINOSULFONYL)-N-[(2,4,6-TRIFLUOROPHENYL)METHYL...)
Affinity DataKd:  3.90nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12022(4-(AMINOSULFONYL)-N-[(3,4,5-TRIFLUOROPHENYL)METHYL...)
Affinity DataKd:  3.90nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12023(N-[(2,3,4,5,6-pentafluorophenyl)methyl]-4-sulfamoy...)
Affinity DataKd:  2nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKd:  660nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM12415(copper(2+) ion 2-[(carboxylatomethyl)[(4-{[2-(4-su...)
Affinity DataKd:  235nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM12416(copper(2+) ion 2-[(carboxylatomethyl)({[(3-{[2-(4-...)
Affinity DataKd:  80nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM12417(copper(2+) ion 2-{2-carboxylato-12-[(4-sulfamoylph...)
Affinity DataKd:  27nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM12418(copper(2+) ion 2-[(carboxylatomethyl)({2-[(4-sulfa...)
Affinity DataKd:  28nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataKd:  45nMpH: 7.6 T: 2°CAssay Description:Dissociation constant of 667-coumate was measured for tight-binding inhibitors of CA II. The formation of the 4-nitrophenol was monitored at 348 nm f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM50163862(4-(1H-benzimidazol-1-ylacetyl)benzenesulfonamide (...)
Affinity DataKd:  4nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM50163863(4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  8.30nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM50163864(3-(1H-benzimidazol-1-ylacetyl)benzenesulfonamide (...)
Affinity DataKd:  4.34E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  1.56E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246549(4-[(2-Methyl-1H-benzimidazol-1-yl)acetyl]benzenesu...)
Affinity DataKd:  6.30nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246550(2-Chloro-4-[(2-methyl-1H-benzimidazol-1-yl)acetyl]...)
Affinity DataKd:  10.5nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246551(3-[(2-Methyl-1H-benzimidazol-1-yl)acetyl]benzenesu...)
Affinity DataKd:  7.69E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM50329831(2-Chloro-5-[(2-methyl-1H-benzimidazol-1-yl)acetyl]...)
Affinity DataKd:  2.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246552(4-{[2-(Hydroxymethyl)-1H-benzimidazol-1-yl]acetyl}...)
Affinity DataKd:  4.17nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246553(2-Chloro-4-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  14.3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246575(3-{[2-(Hydroxymethyl)-1H-benzimidazol-1-yl]acetyl}...)
Affinity DataKd:  4.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM50329830(2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  1.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246554(4-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]benzenesu...)
Affinity DataKd:  100nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246555(4-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...)
Affinity DataKd:  2.86nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246556(3-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]benzenesu...)
Affinity DataKd:  1.67E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM50329822(5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chloro...)
Affinity DataKd:  1.56E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246557(4-[(2-Ethyl-1H-benzimidazol-1-yl)acetyl]benzenesul...)
Affinity DataKd:  5nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246558(2-Chloro-4-[(2-ethyl-1H-benzimidazol-1-yl)acetyl]b...)
Affinity DataKd:  6.25nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246559(3-[(2-Ethyl-1H-benzimidazol-1-yl)acetyl]benzenesul...)
Affinity DataKd:  7.69E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM50329823(2-Chloro-5-[(2-ethyl-1H-benzimidazol-1-yl)acetyl]b...)
Affinity DataKd:  556nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246560(4-[(2-Propyl-1H-benzimidazol-1-yl)acetyl]benzenesu...)
Affinity DataKd:  5.56nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM246561(2-Chloro-4-[(2-propyl-1H-benzimidazol-1-yl)acetyl]...)
Affinity DataKd:  3.57nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
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