Compile Data Set for Download or QSAR
Report error Found 3518 for UniProtKB: P05556
TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199337BDBM50199337(CHEMBL3962660 | US10131658, Compound 6)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2018
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423687BDBM50423687(CHEMBL569442)
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing non activating Ca2+ and Mg2+ by competitive bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199337BDBM50199337(CHEMBL3962660 | US10131658, Compound 6)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2018
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326000BDBM50326000((S)-6-((R)-1-amino-1-oxo-3-phenylpropan-2-ylamino)...)
Affinity DataIC50: 0.0220nMAssay Description:Inhibition of Integrin alpha-4-beta-1-mediated adhesion in human jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423695BDBM50423695(MK-0617 | CHEMBL566154)
Affinity DataIC50: 0.0300nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing non activating Ca2+ and Mg2+ by competitive bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423695BDBM50423695(MK-0617 | CHEMBL566154)
Affinity DataIC50: 0.0300nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing activating Mn2+ by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128319BDBM50128319((S)-3-(4-(3,5-dichloroisonicotinamido)phenyl)-2-((...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of VLA-4 receptor of Jurkat cells in BURJ assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421639BDBM50421639(CHEMBL2110195)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116289BDBM50116289(2-[(1-Benzenesulfonyl-pyrrolidine-2-carbonyl)-amin...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of [125I]VCAM-Ig binding to human integrin alpha4-beta1 (VLA-4) of Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199345BDBM50199345(CHEMBL3893700 | US10131658, Compound 201)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2018
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199345BDBM50199345(CHEMBL3893700 | US10131658, Compound 201)
Affinity DataIC50: 0.0631nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2018
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50562072BDBM50562072(CHEMBL4798264)
Affinity DataIC50: 0.0700nMAssay Description:Displacement of 125I-VCAM-Ig from VLA4 in human Jurkat cells incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105372BDBM50105372((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105372BDBM50105372((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0700nMAssay Description:Antagonistic activity against VLA-4 integrin of human jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124226BDBM50124226(3-(2',6'-Dimethoxy-biphenyl-4-yl)-2-{[1-((S)-4-flu...)
Affinity DataIC50: 0.0700nMAssay Description:Binding affinity towards VLA-4 (alpha4 beta-1) receptor in human Jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128319BDBM50128319((S)-3-(4-(3,5-dichloroisonicotinamido)phenyl)-2-((...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423695BDBM50423695(MK-0617 | CHEMBL566154)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of VLA4 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128319BDBM50128319((S)-3-(4-(3,5-dichloroisonicotinamido)phenyl)-2-((...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of VLA-4 binding in Jurkat cells in the presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423836BDBM50423836(CHEMBL1829034)
Affinity DataIC50: 0.0700nMAssay Description:Antagonist activity at alpha4beta1 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128328BDBM50128328((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of VLA-4 binding in Jurkat cells in the presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128320BDBM50128320((S)-3-{4-[(2-Chloro-4-methoxy-pyridine-3-carbonyl)...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105377BDBM50105377((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0800nMAssay Description:Antagonistic activity against VLA-4 integrin of human jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128328BDBM50128328((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105377BDBM50105377((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105397BDBM50105397((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 0.0800nMAssay Description:Antagonistic activity against VLA-4 integrin of human jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128320BDBM50128320((S)-3-{4-[(2-Chloro-4-methoxy-pyridine-3-carbonyl)...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of VLA-4 binding in Jurkat cells in the presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105397BDBM50105397((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 0.0800nMAssay Description:Displacement of 125I-VCAM-Ig from VLA4 in human Jurkat cells incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105375BDBM50105375((S)-3-(2'-Carbamoyl-biphenyl-4-yl)-2-{[(S)-1-(3,5-...)
Affinity DataIC50: 0.0900nMAssay Description:Antagonistic activity against VLA-4 integrin of human jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128326BDBM50128326((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of VLA-4 binding in Jurkat cells in the presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105377BDBM50105377((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128323BDBM50128323((S)-2-{[(S)-1-(3-Chloro-benzenesulfonyl)-pyrrolidi...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105377BDBM50105377((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of VLA-4 binding in Jurkat cells in the presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128326BDBM50128326((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105401BDBM50105401((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50: 0.0900nMAssay Description:Antagonistic activity against VLA-4 integrin of human jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124282BDBM50124282(2-{[3-((S)-Benzenesulfonyl)-piperidine-3-carbonyl]...)
Affinity DataIC50: 0.0900nMAssay Description:Binding affinity towards VLA-4 (alpha4 beta-1) receptor in human Jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144749BDBM50144749((S)-2-[((S)-1-Benzenesulfonyl-azetidine-2-carboxim...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of 125I-VCAM-Ig from VLA4 in human Jurkat cells incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124242BDBM50124242(2-{[3-((S)-Benzenesulfonyl)-tetrahydro-furan-3-car...)
Affinity DataIC50: 0.100nMAssay Description:Binding affinity towards VLA-4 (alpha4 beta-1) receptor in human Jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117037BDBM50117037((S)-3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-({1...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory binding concentration determined against VCAM/VLA-4 in ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157445BDBM50157445(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105408BDBM50105408((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50: 0.100nMAssay Description:Antagonistic activity against VLA-4 integrin of human jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108208BDBM50108208((S)-2-{[(2S,3S)-1-(3,5-Dichloro-benzenesulfonyl)-3...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128325BDBM50128325(4-[4-((S)-2-Carboxy-2-{[(S)-1-(3,5-dichloro-benzen...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128323BDBM50128323((S)-2-{[(S)-1-(3-Chloro-benzenesulfonyl)-pyrrolidi...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134700BDBM50134700((S)-4-(Benzenesulfonyl-methyl-amino)-4-{(S)-1-carb...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of CS-1 fragment binding to Very late antigen 4 (VLA-4) expressed in Ramos cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108215BDBM50108215((S)-3-(2'-Cyano-biphenyl-4-yl)-2-{[(2S,3S)-1-(3,5-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117004BDBM50117004((S)-3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{[1...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Very late antigen 4/vascular cell adhesion molecule 1 interaction in ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128328BDBM50128328((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50554033BDBM50554033(CHEMBL4794201)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128319BDBM50128319((S)-3-(4-(3,5-dichloroisonicotinamido)phenyl)-2-((...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105390BDBM50105390((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50: 0.100nMAssay Description:Antagonistic activity against VLA-4 integrin of human jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 3518 total ) | Next | Last >>
Jump to: