Compile Data Set for Download or QSAR
Report error Found 1655 for UniProtKB: P05771
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of recombinant human PKCbetaII using myelin basic protein as substrate incubated for 60 mins in presence of 33p-ATP and ATP by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition Protein kinase C (PKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50519062(CHEMBL4442196)
Affinity DataIC50: 0.0900nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIsoform Beta-II of Protein kinase C beta type (PRKCB2)(Human)
Leo Laboratories

US Patent
LigandPNGBDBM239069(US9409931, 8)
Affinity DataEC50:  0.100nMpH: 7.4 T: 2°CAssay Description:On the day at experiment Human Protein Kinase C betaII (PKCbII, Millipore cat#14-496) was incubated with 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

LigandPNGBDBM50519087(CHEMBL3741746)
Affinity DataIC50: 0.130nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519068(CHEMBL4575056)
Affinity DataIC50: 0.140nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519060(CHEMBL4528495)
Affinity DataIC50: 0.150nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM286349(US9518060, Example K7 | US11220518, Ex. No. K7 | U...)
Affinity DataKi:  0.165nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

TargetIsoform Beta-II of Protein kinase C beta type (PRKCB2)(Human)
Leo Laboratories

US Patent
LigandPNGBDBM286349(US9518060, Example K7 | US11220518, Ex. No. K7 | U...)
Affinity DataKi:  0.165nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

LigandPNGBDBM50519083(CHEMBL4538431)
Affinity DataIC50: 0.170nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50391386(CHEMBL2148106)
Affinity DataKi:  0.170nMAssay Description:Inhibition of [3H]PDBu binding to PKCbeta C1A domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50519084(CHEMBL4443190)
Affinity DataIC50: 0.180nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIsoform Beta-II of Protein kinase C beta type (PRKCB2)(Human)
Leo Laboratories

US Patent
LigandPNGBDBM286350(US9518060, Example K8 | US11220518, Ex. No. K8 | U...)
Affinity DataKi:  0.181nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

LigandPNGBDBM286350(US9518060, Example K8 | US11220518, Ex. No. K8 | U...)
Affinity DataKi:  0.181nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM50133236(Tetradecanedioic acid ((S)-5-hydroxymethyl-2-isopr...)
Affinity DataKd:  0.190nMAssay Description:Binding affinity for human PKC beta-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50519087(CHEMBL3741746)
Affinity DataEC50:  0.190nMAssay Description:Agonist activity at Protein kinase C in human U1 cells infected with HIV-1 NL4-3 assessed as induction of HIV-1 p24 production after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50393214(CHEMBL2151411)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PKCbeta-1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIsoform Beta-II of Protein kinase C beta type (PRKCB2)(Human)
Leo Laboratories

US Patent
LigandPNGBDBM239071(US9409931, 7)
Affinity DataEC50:  0.200nMpH: 7.4 T: 2°CAssay Description:On the day at experiment Human Protein Kinase C betaII (PKCbII, Millipore cat#14-496) was incubated with 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

LigandPNGBDBM50092014(Butyric acid (1aS,1bS,4aS,7aS,8R,9S,9aR)-9-butyryl...)
Affinity DataKd:  0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2013
Entry Details Article
PubMed
LigandPNGBDBM50519069(CHEMBL4435580)
Affinity DataIC50: 0.220nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM102423(Bryostatin | Bryostatin 7)
Affinity DataKd:  0.320nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2013
Entry Details Article
PubMed
LigandPNGBDBM50519063(CHEMBL4587471)
Affinity DataIC50: 0.360nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIsoform Beta-II of Protein kinase C beta type (PRKCB2)(Human)
Leo Laboratories

US Patent
LigandPNGBDBM286348(US9518060, Example K6 | US11220518, Ex. No. K6 | U...)
Affinity DataKi:  0.376nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

LigandPNGBDBM286348(US9518060, Example K6 | US11220518, Ex. No. K6 | U...)
Affinity DataKi:  0.376nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM50057514(13-Hydroxymethyl-10-isopropyl-9-methyl-5-octyl-3,9...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC beta expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50258529(CHEMBL449158 | bryostatin 1)
Affinity DataKd:  0.420nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2013
Entry Details Article
PubMed
LigandPNGBDBM50327943(Aplysiatoxin | CHEMBL1256416)
Affinity DataKi:  0.450nMAssay Description:Inhibition of [3H]PDBu binding to PKC beta C1A peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50235282(CHEMBL4077967)
Affinity DataKi:  0.5nMAssay Description:Reversible competitive inhibition of PKCbeta1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
LigandPNGBDBM50519063(CHEMBL4587471)
Affinity DataEC50:  0.550nMAssay Description:Agonist activity at Protein kinase C in human U1 cells infected with HIV-1 NL4-3 assessed as induction of HIV-1 p24 production after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50393218(CHEMBL1996510)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PKCbeta-1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50519068(CHEMBL4575056)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at Protein kinase C in human U1 cells infected with HIV-1 NL4-3 assessed as induction of HIV-1 p24 production after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of protein kinase CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2018
Entry Details

LigandPNGBDBM33971(Sotrastaurin | AEB071 | med.21724, Compound 190)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of PKCbeta1 (unknown origin) by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetIsoform Beta-II of Protein kinase C beta type (PRKCB2)(Human)
Leo Laboratories

US Patent
LigandPNGBDBM286347(US9518060, Example K5 | US11220518, Ex. No. K5 | U...)
Affinity DataKi:  0.683nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

LigandPNGBDBM286347(US9518060, Example K5 | US11220518, Ex. No. K5 | U...)
Affinity DataKi:  0.683nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM50235283(CHEMBL4102228)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PKCbeta1 (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2019
Entry Details Article
PubMed
TargetIsoform Beta-II of Protein kinase C beta type (PRKCB2)(Human)
Leo Laboratories

US Patent
LigandPNGBDBM239070(US9409931, 6)
Affinity DataEC50:  0.800nMpH: 7.4 T: 2°CAssay Description:On the day at experiment Human Protein Kinase C betaII (PKCbII, Millipore cat#14-496) was incubated with 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetIsoform Beta-II of Protein kinase C beta type (PRKCB2)(Human)
Leo Laboratories

US Patent
LigandPNGBDBM286345(US9518060, Example K3 | US11220518, Ex. No. K3 | U...)
Affinity DataKi:  0.912nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

LigandPNGBDBM286345(US9518060, Example K3 | US11220518, Ex. No. K3 | U...)
Affinity DataKi:  0.912nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM50519074(CHEMBL4442856)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519075(CHEMBL4558004)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519072(CHEMBL4580556)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519073(CHEMBL4536366)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519070(CHEMBL4580586)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519071(CHEMBL4585270)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519066(CHEMBL4460926)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519067(CHEMBL4443186)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519064(CHEMBL4586553)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519065(CHEMBL4578026)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50519061(CHEMBL4533733)
Affinity DataIC50: 1nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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