Compile Data Set for Download or QSAR
Report error Found 33 of affinity data for UniProtKB/TrEMBL: P06400
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 370121BDBM370121(6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcy...)
Affinity DataEC50:  19nMAssay Description:Inhibition of RB1 phosphorylation in human OVCAR-3 cells assessed as reduction in phosphorylation at Serine 807/811 residue incubated for 1 hr by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 66nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267481BDBM50267481(6-tert-Butyl-4-{[(4-hydroxy-5-propoxy-pyridin-2-yl...)
Affinity DataIC50: 200nMAssay Description:Inhibition of retinoblastoma susceptibility gene product phosphorylation in human MCF7 cells after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 370258BDBM370258(US10233188, Example 145 | BDBM467153)
Affinity DataIC50: 270nMAssay Description:Inhibition of RB1 phosphorylation in human OVCAR-3 cells assessed as reduction in phosphorylation at Serine 807/811 residue incubated for 1 hr by ELI...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267581BDBM50267581((4Z)-4-[({[1-(3-Furyl)-2-oxo-1,2-dihydropyridin-4-...)
Affinity DataIC50: 370nMAssay Description:Inhibition of retinoblastoma susceptibility gene product phosphorylation in human MCF7 cells after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267255BDBM50267255(4-[(4-Furan-3-yl-3-hydroxy-benzylamino)-methylene]...)
Affinity DataIC50: 610nMAssay Description:Inhibition of retinoblastoma susceptibility gene product phosphorylation in human MCF7 cells after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251835BDBM50251835(CHEMBL4092194)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251835BDBM50251835(CHEMBL4092194)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251836BDBM50251836(CHEMBL4070561)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251866BDBM50251866(CHEMBL4070208)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251841BDBM50251841(CHEMBL4068198)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251850BDBM50251850(CHEMBL4077816)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251837BDBM50251837(CHEMBL4068744)
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251834BDBM50251834(CHEMBL4061653)
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251779BDBM50251779(CHEMBL4076325)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251809BDBM50251809(CHEMBL4075949)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251767BDBM50251767(CHEMBL4092469)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251767BDBM50251767(CHEMBL4092469)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RB1 phosphorylation in human OVCAR-3 cells assessed as reduction in phosphorylation at Serine 807/811 residue incubated for 1 hr by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251781BDBM50251781(CHEMBL4075814)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251843BDBM50251843(CHEMBL4064772)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251761BDBM50251761(CHEMBL4071674)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251768BDBM50251768(CHEMBL4065808)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251768BDBM50251768(CHEMBL4065808)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251806BDBM50251806(CHEMBL4088842)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251815BDBM50251815(CHEMBL4077480)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251816BDBM50251816(CHEMBL4082197)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251814BDBM50251814(CHEMBL4083343)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251849BDBM50251849(CHEMBL4060594)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251808BDBM50251808(CHEMBL4067615)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251848BDBM50251848(CHEMBL4063962)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251780BDBM50251780(CHEMBL4094137)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetRetinoblastoma-associated protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251842BDBM50251842(CHEMBL4082537)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed