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Found 32 of affinity data for UniProtKB/TrEMBL: P06537
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM86694(N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyform...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  2.20nMAssay Description:In vitro antagonist potency in transactivation assay in NIH3T3 cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50409115(LONAPRISAN)
Affinity DataIC50:  16nMAssay Description:In vitro antagonist potency in transactivation assay in NIH3T3 cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50041896(CHEMBL3358954)
Affinity DataIC50:  600nMAssay Description:Agonist activity at GR in mouse RAW cells assessed as suppression of TNF-alpha-induced IL-6 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19223((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  54nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataEC50:  5.70nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19224((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  11nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50165102((S)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  23nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19210((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)
Affinity DataEC50:  3.70nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19220((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  42nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50165105((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  21nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50165101((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  215nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50165106((R)-(5-Chloro-thiophen-2-yl)-[(4aR,5S)-1-(4-fluoro...)
Affinity DataEC50:  34nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50165103((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  45nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataEC50:  3.40nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19220((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  1.21E+3nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19192((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  22nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19224((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  3nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19202((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)
Affinity DataEC50:  5.20nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50165102((S)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  5nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19199((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  15nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50165106((R)-(5-Chloro-thiophen-2-yl)-[(4aR,5S)-1-(4-fluoro...)
Affinity DataEC50:  17nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50165104((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  260nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50165104((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  12nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19202((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)
Affinity DataEC50:  8.30nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM19210((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)
Affinity DataEC50:  17nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50153594(CHEMBL3774855)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of mouse GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50165100((R)-(2,5-Dichloro-thiophen-3-yl)-[(4aR,5S)-1-(4-fl...)
Affinity DataEC50:  120nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50016933(CHEMBL3273977)
Affinity DataKd:  430nMAssay Description:Displacement of 2 x 10'-8 M of [1,2,3-3H]-triamcinolone acetonide from glucocorticoid receptor in soluble fraction of mouse L929 cells after 20 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50016932(CHEMBL3273976)
Affinity DataKd:  7nMAssay Description:Displacement of 2 x 10'-8 M of [1,2,3-3H]-triamcinolone acetonide from glucocorticoid receptor in soluble fraction of mouse L929 cells after 20 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM13775((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataKd:  43nMAssay Description:Displacement of 1 x 10'-8 M of [1,2,3-3H]-triamcinolone acetonide from glucocorticoid receptor in soluble fraction of mouse L929 cells after 20 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(MOUSE)
Taisho Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50016931(CHEBI:31677 | HYDROCORTISONE HEMISUCCINATE | Hydro...)
Affinity DataKd:  190nMAssay Description:Displacement of 1 x 10'-8 M of [1,2,3-3H]-triamcinolone acetonide from glucocorticoid receptor in soluble fraction of mouse L929 cells after 20 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed