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TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507483BDBM50507483(CHEMBL4530379)
Affinity DataKi:  0.00230nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125046BDBM50125046(CHEMBL3623792)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of beta-trypsin (unknown origin) using Bz-FVRpNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124947BDBM50124947(CHEMBL453539)
Affinity DataKi:  0.100nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421510BDBM50421510(CHEMBL239127)
Affinity DataKi:  0.100nMAssay Description:Compound was tested for inhibition of Sunflower beta-trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125045BDBM50125045(CHEMBL3623793)
Affinity DataKi:  0.160nMAssay Description:Inhibition of beta-trypsin (unknown origin) using Bz-FVRpNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533536BDBM50533536(CHEMBL4483694)
Affinity DataKi:  0.160nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-FVRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131780BDBM50131780((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-2-yl...)
Affinity DataKi:  0.300nMAssay Description:In vitro inhibition constant (Ki) against human trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124906BDBM50124906(CHEMBL3623776)
Affinity DataKi:  0.700nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172845BDBM50172845((2-{2-[2-(5-Chloro-2-[1,2,4]triazol-1-yl-benzyl)-o...)
Affinity DataKi:  0.700nMAssay Description:Inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459539BDBM50459539(CHEMBL4206734)
Affinity DataIC50: 1nMAssay Description:Inhibition of trypsin (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172841BDBM50172841((2-{2-[2-(5-Chloro-2-[1,2,4]triazol-1-yl-benzyl)-o...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50513213BDBM50513213(CHEMBL3344303)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate preincubated with enzyme for 15 mins followed by addition of substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172829BDBM50172829([2-(5-Chloro-2-[1,2,4]triazol-1-yl-benzyl)-oxazolo...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172831BDBM50172831([2-(5-Chloro-2-[1,2,4]triazol-1-yl-benzyl)-oxazolo...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172832BDBM50172832(2-(2-{2-[2-(5-Chloro-2-[1,2,4]triazol-1-yl-benzyl)...)
Affinity DataKi:  1.60nMAssay Description:Inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50513215BDBM50513215(CHEMBL4561509)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate preincubated with enzyme for 15 mins followed by addition of substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172826BDBM50172826([2-(5-Chloro-2-[1,2,4]triazol-1-yl-benzyl)-oxazolo...)
Affinity DataKi:  1.60nMAssay Description:Inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110387BDBM50110387(4-{2-[(S)-5-((S)-2,3-Dihydro-benzofuran-5-sulfonyl...)
Affinity DataKi:  2.5nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50513214BDBM50513214(CHEMBL4586045)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate preincubated with enzyme for 15 mins followed by addition of substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172830BDBM50172830([2-(5-Chloro-2-[1,2,4]triazol-1-yl-benzyl)-oxazolo...)
Affinity DataKi:  2.90nMAssay Description:Inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110389BDBM50110389(4-{3-[(S)-3-(2,3-Dihydro-benzofuran-5-sulfonylamin...)
Affinity DataKi:  3.20nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096100BDBM50096100(2-(3-Carbamimidoyl-phenyl)-5-trifluoromethyl-2H-py...)
Affinity DataKi:  3.40nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097624BDBM50097624(3-(3-Carbamimidoyl-phenyl)-3H-[1,2,3]triazole-4-ca...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50424712BDBM50424712(Camostat Mesilate | Foipan | CAMOSTAT)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate preincubated with enzyme for 15 mins followed by addition of substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514081BDBM50514081(CHEMBL4471466)
Affinity DataKi:  3.60nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514081BDBM50514081(CHEMBL4471466)
Affinity DataKi:  3.60nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096111BDBM50096111(2-(3-Carbamimidoyl-phenyl)-5-trifluoromethyl-2H-py...)
Affinity DataKi:  3.90nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096097BDBM50096097(2-(3-Carbamimidoyl-phenyl)-5-trifluoromethyl-2H-py...)
Affinity DataKi:  4nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096110BDBM50096110(2-(3-Carbamimidoyl-phenyl)-5-trifluoromethyl-2H-py...)
Affinity DataKi:  4.30nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096099BDBM50096099(2-(3-Carbamimidoyl-phenyl)-5-methyl-2H-pyrazole-3-...)
Affinity DataKi:  4.60nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110393BDBM50110393(5-{3-[(S)-3-(2,3-Dihydro-benzofuran-5-sulfonylamin...)
Affinity DataKi:  5.90nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097626BDBM50097626(CHEMBL160489 | CHEMBL332157 | 1-(3-Carbamimidoyl-p...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity towards human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507482BDBM50507482(CHEMBL4531700)
Affinity DataKi:  6.90nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-FVR-pNA as substrate preincubated for 30 mins followed by substrate addition and measured for 7 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533535BDBM50533535(CHEMBL4440685)
Affinity DataKi:  6.90nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-FVRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172847BDBM50172847([2-(5-Chloro-2-[1,2,4]triazol-1-yl-benzyl)-oxazolo...)
Affinity DataKi:  6.90nMAssay Description:Inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110374BDBM50110374(4-{3-[(S)-3-(2,3-Dihydro-benzofuran-5-sulfonylamin...)
Affinity DataKi:  7.60nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125048BDBM50125048(CHEMBL3623788)
Affinity DataKi:  8nMAssay Description:Inhibition of beta-trypsin (unknown origin) using Bz-FVRpNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110391BDBM50110391(4-[3-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl...)
Affinity DataKi:  8.30nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520867BDBM50520867(CHEMBL4441346)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human trypsin preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096090BDBM50096090(5-Butyl-2-(3-carbamimidoyl-phenyl)-2H-pyrazole-3-c...)
Affinity DataKi:  11nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110392BDBM50110392(4-{3-[(S)-3-(3,4-Dimethoxy-benzenesulfonylamino)-2...)
Affinity DataKi:  12nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110375BDBM50110375(4-{3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-az...)
Affinity DataKi:  12nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096091BDBM50096091(2-(3-Carbamimidoyl-phenyl)-5-methyl-2H-pyrazole-3-...)
Affinity DataKi:  13nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096085BDBM50096085(2-(3-Carbamimidoyl-phenyl)-5-methyl-2H-pyrazole-3-...)
Affinity DataKi:  15nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096095BDBM50096095(2-(3-Carbamimidoyl-phenyl)-2H-pyrazole-3-carboxyli...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096095BDBM50096095(2-(3-Carbamimidoyl-phenyl)-2H-pyrazole-3-carboxyli...)
Affinity DataKi:  15nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 12751BDBM12751(CHEMBL152854 | 1-(3-carbamimidoylphenyl)-3-methyl-...)
Affinity DataKi:  16nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 12751BDBM12751(CHEMBL152854 | 1-(3-carbamimidoylphenyl)-3-methyl-...)
Affinity DataKi:  16nMAssay Description:Inhibition of human trypsin using S-2222 as substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110394BDBM50110394([amino({[(4S)-4-carboxy-4-{2-[(3S)-3-({[2-(methoxy...)
Affinity DataKi:  16nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 12751BDBM12751(CHEMBL152854 | 1-(3-carbamimidoylphenyl)-3-methyl-...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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