Compile Data Set for Download or QSAR
Report error Found 5958 of affinity data for UniProtKB/TrEMBL: P10275
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM334271(2-Hydroxy-2- methyl- pentanoic acid (2-bromo-pyrid...)
Affinity DataKd:  75nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM334272(2-Hydroxy-2- methyl-hexanoic acid (2-bromo- 6-meth...)
Affinity DataKd:  30nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM334273(2-Butyl-2- hydroxy-hexanoic acid (2-bromo- pyridin...)
Affinity DataKd:  15nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM334274(N-(2-Bromo-pyridin- 4-yl)-2-hydroxy-4- (4-methoxy-...)
Affinity DataKd:  300nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM334275(N-(2-Bromo- pyridin-4-yl)-2- hydroxy-2-phenyl- pro...)
Affinity DataKd:  100nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM334276(2-Hydroxy-2,4- dimethyl-pentanoic acid (2-bromo-6-...)
Affinity DataKd:  20nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM334277(N-(2-Bromo-pyridin- 4-yl)-2-hydroxy- 2-methyl-4-ph...)
Affinity DataKd:  100nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM334278(4-(2-Hydroxy-2- methyl- pentanoylamino)- pyridine-...)
Affinity DataKd:  6.00E+3nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM35910(flufenamic acid analogue, 36)
Affinity DataEC50:  3.00E+4nMpH: 7.2 T: 2°CAssay Description:AR functionality was determined by fluorescence polarization (excitation @485 nm, emission @ 530 nm) assay, which measures fluorescently labeled SRC2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM35911(flufenamic acid analogue, 37)
Affinity DataEC50:  3.90E+4nMpH: 7.2 T: 2°CAssay Description:AR functionality was determined by fluorescence polarization (excitation @485 nm, emission @ 530 nm) assay, which measures fluorescently labeled SRC2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM35912(flufenamic acid analogue, 38)
Affinity DataEC50:  4.25E+4nMpH: 7.2 T: 2°CAssay Description:AR functionality was determined by fluorescence polarization (excitation @485 nm, emission @ 530 nm) assay, which measures fluorescently labeled SRC2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM35913(flufenamic acid analogue, 39)
Affinity DataEC50:  4.85E+4nMpH: 7.2 T: 2°CAssay Description:AR functionality was determined by fluorescence polarization (excitation @485 nm, emission @ 530 nm) assay, which measures fluorescently labeled SRC2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM35914(flufenamic acid analogue, 40)
Affinity DataEC50:  5.40E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM35908(flufenamic acid analogue, 41 | flufenamic acid ana...)
Affinity DataEC50:  5.60E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM35916(flufenamic acid analogue, 42)
Affinity DataEC50:  6.40E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM35917(flufenamic acid analogue, 43)
Affinity DataEC50:  7.55E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM35918(flufenamic acid analogue, 44)
Affinity DataEC50:  8.30E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM35919(flufenamic acid analogue, 45)
Affinity DataEC50:  9.30E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataEC50:  6.70E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor [646-919](Human)
Karlsruhe Institute of Technology

LigandPNGBDBM227645(MAQRGGARRPRGDRERLGSR | Bag-1L (1-20))
Affinity DataKd:  2.00E+3nMpH: 6.5Assay Description:For the fluorescence polarization experiments, 5 nM fluorescently labeled Bag-1L (Bag-1L(1-20), fluorescein isothiocyanate (FITC)-MAQRGGARRPRGDRERLGS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2017
Entry Details Article
PubMed
TargetAndrogen receptor [646-919](Human)
Karlsruhe Institute of Technology

LigandPNGBDBM227646(RGAAAGARRPRMKKKTRRRS | Bag-1L (61-80))
Affinity DataKd:  3.30E+3nMpH: 6.5Assay Description:For the fluorescence polarization experiments, 5 nM fluorescently labeled Bag-1L (Bag-1L(1-20), fluorescein isothiocyanate (FITC)-MAQRGGARRPRGDRERLGS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2017
Entry Details Article
PubMed
TargetAndrogen receptor [646-919](Human)
Karlsruhe Institute of Technology

LigandPNGBDBM227647(HDSKGQTKLLQLLTTKSDQM | SCR-2 peptide)
Affinity DataKd:  2.80E+3nMpH: 6.5Assay Description:For the fluorescence polarization experiments, 5 nM fluorescently labeled Bag-1L (Bag-1L(1-20), fluorescein isothiocyanate (FITC)-MAQRGGARRPRGDRERLGS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2017
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM696507(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to AR was determined using the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay kit (brand: Thermo, Cat....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM696509(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to AR was determined using the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay kit (brand: Thermo, Cat....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM696511(Synthesis of (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to AR was determined using the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay kit (brand: Thermo, Cat....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM696513(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to AR was determined using the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay kit (brand: Thermo, Cat....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM696514(Synthesis of (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to AR was determined using the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay kit (brand: Thermo, Cat....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent

TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM737487(US20250136619, Compound I-21)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM737488(US20250136619, Compound I-34)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50407398(CB7630 | Zytiga | ABIRATERONE ACETATE)
Affinity DataEC50:  1.71E+4nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataEC50:  420nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50240230(CHEMBL4092687)
Affinity DataEC50:  2.81E+4nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50240229(CHEMBL4084182)
Affinity DataEC50:  1.27E+4nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataEC50:  9.50E+3nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242300(CHEMBL4074501)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242302(CHEMBL4101935)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50238125(CHEMBL4090028)
Affinity DataEC50:  0.190nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50238127(CHEMBL4092535)
Affinity DataEC50:  0.290nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242306(CHEMBL4100278)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242307(CHEMBL4085514)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242308(CHEMBL4072533)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242309(CHEMBL4067691)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242312(CHEMBL4063939)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242313(CHEMBL4093265)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM18161(DHT | Dihydrotestosterone | [3H]DHT | (5alpha,17be...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242310(CHEMBL4082265)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242314(CHEMBL4083012)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242305(CHEMBL4071751)
Affinity DataEC50:  810nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242297(CHEMBL4088914)
Affinity DataEC50:  4.70nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50242298(CHEMBL4059588)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human AR expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
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