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Report error Found 959 for UniProtKB: P10827
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataKd:  1.20nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2011
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM36488(CO22)
Affinity DataKd:  286nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2011
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataKd:  0.0580nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2011
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  2.40nMAssay Description:TRE-driven dual-luciferase reporter assay in human bone osteosarcoma epithelial (U2OS) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2011
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM36488(CO22)
Affinity DataEC50:  3.87E+3nMAssay Description:TRE-driven dual-luciferase reporter assay in human bone osteosarcoma epithelial (U2OS) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2011
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  34nMAssay Description:TRE-driven dual-luciferase reporter assay in human bone osteosarcoma epithelial (U2OS) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2011
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  11nMAssay Description:TRE-driven dual-luciferase reporter assay in human uterine cervical cancer (Hela) cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2011
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  2.40nMAssay Description:TRE-driven dual-luciferase reporter assay in human uterine cervical cancer (Hela) cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2011
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataKd:  0.0580nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM50115668([4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phe...)
Affinity DataKd:  0.440nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM50130595(Dimethyl-isopropyl-T3 (DIMIT) | CHEMBL105983 | 2-A...)
Affinity DataKd:  9.70nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  1.01nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM50115668([4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phe...)
Affinity DataEC50:  74.7nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM426634(US10544075, Compound JD-20)
Affinity DataEC50:  7.96nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM426635(US10544075, Compound JD-21)
Affinity DataEC50:  7.82nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466857(US10800767, Example 16 | US10800767, Example 1)
Affinity DataEC50:  49.5nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466858(US10800767, Example 2)
Affinity DataEC50: >5.00E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466859(US10800767, Example 3-P1)
Affinity DataEC50:  75.9nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466860(US10800767, Example 3-P2)
Affinity DataEC50:  817nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466861(US10800767, Example 14 | US10800767, Example 4)
Affinity DataEC50:  314nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466862(US10800767, Example 15 | US10800767, Example 5)
Affinity DataEC50:  469nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466863(US10800767, Example 6)
Affinity DataEC50:  78nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466864(US10800767, Example 7)
Affinity DataEC50:  473nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466865(US10800767, Example 8)
Affinity DataEC50:  2.30E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466866(US10800767, Example 9)
Affinity DataEC50:  126nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466867(US10800767, Example 11)
Affinity DataEC50:  192nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466868(US10800767, Example 12)
Affinity DataEC50:  152nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466869(US10800767, Example 23 | US10800767, Example 13)
Affinity DataEC50:  1.63E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466861(US10800767, Example 14 | US10800767, Example 4)
Affinity DataEC50:  549nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466862(US10800767, Example 15 | US10800767, Example 5)
Affinity DataEC50:  102nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466857(US10800767, Example 16 | US10800767, Example 1)
Affinity DataEC50:  82.4nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466873(US10800767, Example 17)
Affinity DataEC50: >5.00E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466874(US10800767, Example 18)
Affinity DataEC50:  550nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466875(US10800767, Example 19)
Affinity DataEC50:  1.93E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466876(US10800767, Example 20)
Affinity DataEC50: >5.00E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466877(US10800767, Example 21)
Affinity DataEC50: >5.00E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466878(US10800767, Example 22)
Affinity DataEC50:  898nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466869(US10800767, Example 23 | US10800767, Example 13)
Affinity DataEC50:  1.32E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466880(US10800767, Example 24)
Affinity DataEC50:  2.05E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466881(US10800767, Example 25)
Affinity DataEC50:  2.42E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466882(US10800767, Example 27 | US10800767, Example 26)
Affinity DataEC50:  699nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466882(US10800767, Example 27 | US10800767, Example 26)
Affinity DataEC50:  144nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466884(US10800767, Example 28)
Affinity DataEC50:  4.27E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466885((P1 and P2): N-(3,5-dichloro-4-((5-(1-hydroxyethyl...)
Affinity DataEC50:  4.34E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466886(US10800767, Example 29P1)
Affinity DataEC50: >5.00E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466887(US10800767, Example 29P2)
Affinity DataEC50:  1.76E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466888(US10800767, Example 30)
Affinity DataEC50:  3.11E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466889(US10800767, Example 31)
Affinity DataEC50: >5.00E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466890(N-(3,5-dichloro-4-((5-(1-hydroxypropyl)-6-oxo-1,6-...)
Affinity DataEC50:  1.55E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
University of California San Francisco

LigandPNGBDBM466891(US10800767, Example 32P1)
Affinity DataEC50:  4.23E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

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