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TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471778(CHEMBL332805)
Affinity DataEC50: >5.00E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50214093(CHEMBL281022)
Affinity DataEC50: >2.50E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50214094(CHEMBL30053)
Affinity DataEC50: >2.10E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471779(CHEMBL121192)
Affinity DataEC50:  2.00E+4nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50213997(CHEMBL30099)
Affinity DataEC50: >2.20E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50213996(CHEMBL30104)
Affinity DataEC50:  550nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471780(CHEMBL333026)
Affinity DataEC50:  9.00E+4nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50214149(CHEMBL29836)
Affinity DataEC50: >2.20E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471781(CHEMBL121442)
Affinity DataEC50:  1.60E+3nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471782(CHEMBL120915)
Affinity DataEC50:  5.10E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471783(CHEMBL121666)
Affinity DataEC50:  500nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50214091(CHEMBL27233)
Affinity DataEC50:  330nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50213998(CHEMBL27542)
Affinity DataEC50: >2.40E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50213995(CHEMBL25908)
Affinity DataEC50: >2.30E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471784(CHEMBL122716)
Affinity DataEC50:  1.00E+4nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50214092(CHEMBL27064)
Affinity DataEC50: >2.60E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471785(CHEMBL333641)
Affinity DataEC50: >2.20E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471786(CHEMBL434812)
Affinity DataEC50: >4.80E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471787(CHEMBL330996)
Affinity DataEC50: >2.70E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  720nMAssay Description:In vitro inhibitior of human DNA topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50213999(CHEMBL287205)
Affinity DataEC50: >2.60E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471788(CHEMBL121547)
Affinity DataEC50: >2.10E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50213994(CHEMBL280609)
Affinity DataEC50: >2.40E+5nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50214148(CHEMBL283395)
Affinity DataEC50:  3.00E+3nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471908(CHEMBL142016)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471909(CHEMBL433875)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471908(CHEMBL142016)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471910(CHEMBL344226)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471911(CHEMBL342844)
Affinity DataEC50: >1.00E+3nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471912(CHEMBL139335)
Affinity DataEC50:  5.60E+3nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471913(NK-611)
Affinity DataEC50:  5.60E+4nMAssay Description:In vitro inhibitory activity against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471914(CHEMBL336443)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471909(CHEMBL433875)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471915(CHEMBL434650)
Affinity DataEC50: >1.00E+3nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataEC50:  5.60E+4nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50471916(CHEMBL140036)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50045698(WIN-57294 | 1-Cyclopropyl-7-(2,6-dimethyl-pyridin-...)
Affinity DataEC50:  7.60E+3nMAssay Description:Inhibitory activity in a DNA cleavage assay using HeLa DNA topoisomerase II yielding its effective concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505822(CHEMBL4514715)
Affinity DataEC50:  4.70E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505822(CHEMBL4514715)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505824(CHEMBL4476462)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505832(CHEMBL4462930)
Affinity DataEC50:  9.50E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505828(CHEMBL4527023)
Affinity DataEC50:  1.90E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505823(CHEMBL4584155)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505833(CHEMBL4564777)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505830(CHEMBL4474912)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505821(CHEMBL4457343)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505828(CHEMBL4527023)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505823(CHEMBL4584155)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505833(CHEMBL4564777)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505824(CHEMBL4476462)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
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