Compile Data Set for Download or QSAR
Report error Found 235 of affinity data for UniProtKB/TrEMBL: P15381
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50336640((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]nitrendipine binding to calcium channels in Rabbit cardiac muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227241(CHEMBL1202817)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]nitrendipine binding to calcium channels in Rabbit cardiac muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002644(CHEMBL78656 | 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-...)
Affinity DataIC50: 1.40nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50336640((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...)
Affinity DataIC50: 2.90nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002628(CHEMBL78651 | 4-(2,3-Dichloro-phenyl)-2,6-dimethyl...)
Affinity DataIC50: 2.90nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002603(CHEMBL81326 | 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-...)
Affinity DataIC50: 3.30nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002613(CHEMBL312276 | 2,6-Dimethyl-4-(2-trifluoromethyl-p...)
Affinity DataIC50: 3.60nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002626(CHEMBL80771 | 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-...)
Affinity DataIC50: 5.10nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002607(CHEMBL432933 | 4-(2,3-Dichloro-phenyl)-2,6-dimethy...)
Affinity DataIC50: 5.10nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317833(3-methyl 5-(3-phenylbutyl)2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317821(3-(3,4-difluorobenzyl)5-methyl 2,6-dimethyl-4-(3-n...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002600(CHEMBL312103 | 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4...)
Affinity DataIC50: 7.80nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317776(dimethyl 2,6-dimethyl-4-(2-(methylthio)phenyl)-1,4...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317802(3-allyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317775(diethyl 2,6-dimethyl-4-(2-(methylthio)phenyl)-1,4-...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317831(3-(4-chlorophenethyl)5-methyl 2,6-dimethyl-4-(3-ni...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317836(3-methyl 5-(3-phenoxypropyl)2,6-dimethyl-4-(3-nitr...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317835(3-(2-(benzyloxy)ethyl)5-methyl 2,6-dimethyl-4-(3-n...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317794(diethyl 2-(acetoxymethyl)-6-methyl-4-(3-nitropheny...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317793(diethyl 2-(chloromethyl)-6-methyl-4-(3-nitrophenyl...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317813(3-ethyl 5-(2-(methacryloyloxy)ethyl)2,6-dimethyl-4...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317817(3-cyclohex-2-enyl 5-methyl 2,6-dimethyl-4-(3-nitro...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002643(CHEMBL79740 | 4-(2-Chloro-phenyl)-2,6-dimethyl-1,4...)
Affinity DataIC50: 10nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317832(3-methyl 5-(4-phenylbutyl)2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317822(3-methyl 5-(2,4,6-trichlorobenzyl)2,6-dimethyl-4-(...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317825(3-benzo[d][1,3]dioxol-5-ylmethyl 5-methyl 2,6-dime...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002635(CHEMBL311556 | 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4...)
Affinity DataIC50: 13nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317790(3-ethyl 5-methyl 6-(methoxymethyl)-2-methyl-4-(3-n...)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002621(CHEMBL78790 | 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-...)
Affinity DataIC50: 15nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317840(diethyl 4-(2,3-difluorophenyl)-2,6-dimethyl-1,4-di...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317803(3-allyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317810(3-methyl 5-(2,2,2-trifluoroethyl)2,6-dimethyl-4-(3...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317808(3-ethyl 5-(2-methoxyethyl)2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317834(3-(4-(4-methoxyphenyl)butyl)5-methyl 2,6-dimethyl-...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317787(diethyl 2-methyl-4-(3-nitrophenyl)-6-propyl-1,4-di...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317829(3-(2-(2-chlorophenoxy)ethyl)5-methyl 2,6-dimethyl-...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317826(3-furan-2-ylmethyl 5-methyl 2,6-dimethyl-4-(3-nitr...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317841(diethyl 4-(2,4-difluorophenyl)-2,6-dimethyl-1,4-di...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317788(diethyl 2-butyl-6-methyl-4-(3-nitrophenyl)-1,4-dih...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317820(3-(3-fluorobenzyl)5-methyl 2,6-dimethyl-4-(3-nitro...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317798(diethyl 2-(2-cyanovinyl)-6-methyl-4-(3-nitrophenyl...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317806(3-methyl 5-(3-methylbut-3-enyl)2,6-dimethyl-4-(3-n...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002580(CHEMBL80501 | 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-...)
Affinity DataIC50: 25nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317815(3-benzyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002631(CHEMBL78944 | 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-...)
Affinity DataIC50: 25nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317804(3-allyl 5-ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317783(S-(+)-3-(2-cyanoethyl)5-methyl 2,6-dimethyl-4-(3-n...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317809(3-(2-chloroethyl)5-methyl 2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317807(3-cyclopropylmethyl 5-methyl 2,6-dimethyl-4-(3-nit...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317827(3-methyl 5-thiophen-2-ylmethyl 2,6-dimethyl-4-(3-n...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
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