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Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650862(US20240043440, Example 58B)
Affinity DataIC50: 0.130nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650874(US20240043440, Example 64A)
Affinity DataIC50: 0.360nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650800(US20240043440, Example 16 | US20240043440, Example...)
Affinity DataIC50: 0.400nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (5 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650868(US20240043440, Example 61A)
Affinity DataIC50: 0.440nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650855(US20240043440, Example 54A)
Affinity DataIC50: 0.450nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650883(US20240043440, Example 68A)
Affinity DataIC50: 0.480nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM556317(US11345702, Table 1.35 | US20230390274, Compound A...)
Affinity DataIC50: 0.5nMAssay Description:A hydroxyprostaglandin dehydrogenase inhibition screening biochemical assay can be performed to assess the synthesized inhibitors provided herein. Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650865(US20240043440, Example 60A)
Affinity DataIC50: 0.5nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM740652(US20250154162, Example 21)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM740654(US20250154162, Example 23)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM740655(US20250154162, Example 24)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM740656(US20250154162, Example 25)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM740664(US20250154162, Example 33)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM740678(US20250154162, Example 47)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM740691(US20250154162, Example 60)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650881(US20240043440, Example 67A)
Affinity DataIC50: 0.520nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650892(US20240043440, Example 74A)
Affinity DataIC50: 0.520nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650861(US20240043440, Example 58A)
Affinity DataIC50: 0.550nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650871(US20240043440, Example 62A)
Affinity DataIC50: 0.560nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650908(US20240043440, Example 86A)
Affinity DataIC50: 0.560nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650847(US20240043440, Example 50A)
Affinity DataIC50: 0.570nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650834(US20240043440, Example 43A)
Affinity DataIC50: 0.580nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650832(US20240043440, Example 42B)
Affinity DataIC50: 0.590nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650877(US20240043440, Example 65A)
Affinity DataIC50: 0.590nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM556286(US11345702, Table 1.4 | US20230390274, Compound A-...)
Affinity DataIC50: 0.600nMAssay Description:A hydroxyprostaglandin dehydrogenase inhibition screening biochemical assay can be performed to assess the synthesized inhibitors provided herein. Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650841(US20240043440, Example 47A)
Affinity DataIC50: 0.650nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650838(US20240043440, Example 46A)
Affinity DataIC50: 0.700nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650826(US20240043440, Example 39A)
Affinity DataIC50: 0.720nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650843(US20240043440, Example 48A)
Affinity DataIC50: 0.720nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650829(US20240043440, Example 41A)
Affinity DataIC50: 0.730nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650852(US20240043440, Example 52A)
Affinity DataIC50: 0.75nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US9789116, SW033291 | US10301320, ID SW033291 | US...)
Affinity DataIC50: 0.760nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650796(US20240043440, Example 12 | US20240043440, Example...)
Affinity DataIC50: 0.760nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (5 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650823(US20240043440, Example 38A)
Affinity DataIC50: 0.760nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650901(US20240043440, Example 81)
Affinity DataIC50: 0.760nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650911(US20240043440, Example 89A)
Affinity DataIC50: 0.770nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650854(US20240043440, Example 54)
Affinity DataIC50: 0.820nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650886(US20240043440, Example 70)
Affinity DataIC50: 0.880nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650863(US20240043440, Example 59)
Affinity DataIC50: 0.910nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650888(US20240043440, Example 72)
Affinity DataIC50: 0.930nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347364(US9789116, SW206980 | US10301320, ID SW206980 | US...)
Affinity DataIC50: 0.970nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347365(US9789116, SW206992 | US10301320, ID SW206992 | US...)
Affinity DataIC50: 0.970nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347364(US9789116, SW206980 | US10301320, ID SW206980 | US...)
Affinity DataIC50: 0.970nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650887(US20240043440, Example 71)
Affinity DataIC50: 0.980nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650849(US20240043440, Example 51)
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650857(US20240043440, Example 55)
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650889(US20240043440, Example 73)
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650897(US20240043440, Example 78-A)
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650899(US20240043440, Example 79-A)
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650902(US20240043440, Example 82)
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

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