Compile Data Set for Download or QSAR
Report error Found 2056 for UniProtKB: P17252
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128285BDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of recombinant human PKCalpha using myelin basic protein as substrate incubated for 60 mins in presence of 33p-ATP and ATP by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3149BDBM3149(Acyclic Balanol Analog (-)-1 | 2-{[2,6-dihydroxy-4...)
Affinity DataIC50: 0.0740nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition Protein kinase C (PKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50519062BDBM50519062(CHEMBL4442196)
Affinity DataIC50: 0.0900nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251513BDBM251513(US9452998, 62)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PKCalpha (unknown origin) incubated for 15 mins in presence of 33P-ATP by Topcount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251522BDBM251522(US9452998, 71)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PKCalpha (unknown origin) incubated for 15 mins in presence of 33P-ATP by Topcount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642779BDBM50642779(CHEMBL5573642)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PKCalpha (unknown origin) incubated for 15 mins in presence of 33P-ATP by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251528BDBM251528(US9452998, 77)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PKCalpha (unknown origin) incubated for 15 mins in presence of 33P-ATP by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251508BDBM251508(US9452998, 57)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PKCalpha (unknown origin) incubated for 15 mins in presence of 33P-ATP by Topcount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251491BDBM251491(US9452998, 51 | US9452998, 40)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251496BDBM251496(US9452998, 45)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251574BDBM251574(US9452998, Table 4 Compound 4)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251497BDBM251497(US9452998, 46)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251572BDBM251572(US9452998, Table 4 Compound 2)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50519087BDBM50519087(CHEMBL3741746)
Affinity DataIC50: 0.130nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251506BDBM251506(US9452998, 55)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251507BDBM251507(US9452998, 76 | US9452998, 56)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251515BDBM251515(US9452998, 64)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251512BDBM251512(US9452998, 61)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251513BDBM251513(US9452998, 62)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251508BDBM251508(US9452998, 57)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251509BDBM251509(US9452998, 58)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251458BDBM251458(US9452998, 7)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251522BDBM251522(US9452998, 71)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251523BDBM251523(US9452998, 78 | US9452998, 72)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251455BDBM251455(US9452998, 4)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251516BDBM251516(US9452998, 65)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251517BDBM251517(US9452998, 77 | US9452998, 66)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251517BDBM251517(US9452998, 77 | US9452998, 66)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251523BDBM251523(US9452998, 78 | US9452998, 72)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251507BDBM251507(US9452998, 76 | US9452998, 56)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251524BDBM251524(US9452998, 73)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251529BDBM251529(US9452998, 78)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of PKCalpha (unknown origin) incubated for 15 mins in presence of 33P-ATP by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251544BDBM251544(US9452998, 93)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 86434BDBM86434(NSC_105100 | CAS_105100 | 12-Deoxyphorbol 13-pheny...)
Affinity DataKi:  0.140nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50519068BDBM50519068(CHEMBL4575056)
Affinity DataIC50: 0.140nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251511BDBM251511(US9452998, 60)
Affinity DataIC50: 0.140nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099646BDBM50099646(Ingenol-3-bezoate | 5,6-dihydroxy-7-hydroxymethyl-...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]PDBU from protein kinase C-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251573BDBM251573(US9452998, Table 4 Compound 3)
Affinity DataIC50: 0.150nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50519060BDBM50519060(CHEMBL4528495)
Affinity DataIC50: 0.150nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251540BDBM251540(US9452998, 89)
Affinity DataIC50: 0.160nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50519083BDBM50519083(CHEMBL4538431)
Affinity DataIC50: 0.170nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251493BDBM251493(US9452998, 42)
Affinity DataIC50: 0.170nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50519084BDBM50519084(CHEMBL4443190)
Affinity DataIC50: 0.180nMAssay Description:Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251501BDBM251501(US9452998, 50)
Affinity DataIC50: 0.190nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251575BDBM251575(US9452998, Table 4 Compound 5)
Affinity DataIC50: 0.190nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50519087BDBM50519087(CHEMBL3741746)
Affinity DataEC50:  0.190nMAssay Description:Agonist activity at Protein kinase C in human U1 cells infected with HIV-1 NL4-3 assessed as induction of HIV-1 p24 production after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251504BDBM251504(US9452998, 53)
Affinity DataIC50: 0.200nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50057512BDBM50057512((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...)
Affinity DataKi:  0.200nMAssay Description:Binding Affinity against protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Lilly Research Labs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251491BDBM251491(US9452998, 51 | US9452998, 40)
Affinity DataIC50: 0.200nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

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