Affinity DataIC50: 0.100nMAssay Description:Inhibition of full length human recombinant PTPN2 by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of His-tagged PTPN2 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of His-tagged PTPN2 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of His-tagged PTPN2 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of His-tagged PTPN2 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Binding affinity to PTPN2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Binding affinity to PTPN2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to PTPN2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:A PhosphoSens kinase assay was performed as described by the vendor (AssayQuant Technologies, Marlborough, MA). Briefly, 1000x solutions of compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human recombinant PTPN2 using DiFMUP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length human recombinant PTPN2 by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of full-length human recombinant PTPN2 incubated for 20 mins by mobile shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human PTPN2 extracted from Escherichia coli BL21 (DE3) by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant TCPTPMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant TCPTPMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant TCPTPMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant TCPTPMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human recombinant PTPN2 using DiFMUP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair






























3D Structure (crystal)








