Compile Data Set for Download or QSAR
Report error Found 127 of affinity data for UniProtKB/TrEMBL: P18433
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131550BDBM50131550((S)-4-((S)-1-amino-3-(4-(difluoro(phosphono)methyl...)
Affinity DataKi:  24nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13976BDBM13976(CHEMBL116605 | Aminobenzoic acid analog 5)
Affinity DataKi:  65nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13976BDBM13976(CHEMBL116605 | Aminobenzoic acid analog 5)
Affinity DataKi:  65nMAssay Description:Inhibitory constant of compound against T cell protein tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131555BDBM50131555(2-(4-(2-acetamido-3-(4-(1-carboxy-N-(2-carboxyphen...)
Affinity DataKi:  73nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131553BDBM50131553(2-[(4-{2-Acetylamino-2-[4-(3-hydroxy-2-nitro-pheno...)
Affinity DataKi:  120nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131547BDBM50131547(2-[4-(2-Acetylamino-3-{4-[(2-carboxy-phenyl)-oxaly...)
Affinity DataKi:  230nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15819BDBM15819(1:1 mixture of diastereomers | CHEMBL55243 | 2-[(4...)
Affinity DataKi:  380nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131545BDBM50131545((S)-2-(N-(4-(2-(allyloxycarbonylamino)-3-(4-(3-hyd...)
Affinity DataKi:  470nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131546BDBM50131546(2-[(4-{2-Acetylamino-2-[4-(3-hydroxy-2-methylcarba...)
Affinity DataKi:  830nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131548BDBM50131548(4-[4-(2-Acetylamino-3-{4-[(2-carboxy-phenyl)-oxaly...)
Affinity DataKi:  840nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131551BDBM50131551(2-carboxy(2-ethyl-4-{2-methylcarboxamido-2-[4-(2-m...)
Affinity DataKi:  860nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188776BDBM50188776({4-[2-BENZYL-3-METHOXY-2-(METHOXYCARBONYL)-3-OXOPR...)
Affinity DataIC50: 900nMAssay Description:Inhibition HPTPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131544BDBM50131544(6-[4-(2-Acetylamino-3-{4-[(2-carboxy-phenyl)-oxaly...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326559BDBM50326559(4-(9,10-dioxo-4-(phenylamino)-5,8,9,10-tetrahydroa...)
Affinity DataIC50: 3.60E+3nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326562BDBM50326562(8-phenyl-1-thia-4,8-diazaspiro[4.5]decane-3-carbox...)
Affinity DataIC50: 4.00E+3nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326563BDBM50326563(2-amino-3-(3,5-dibromo-4-hydroxyphenyl)propanoic a...)
Affinity DataIC50: 4.60E+3nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326557BDBM50326557(NSC45576, 2 | CHEMBL1253920 | (E)-5-((2-hydroxynap...)
Affinity DataIC50: 5.50E+3nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326559BDBM50326559(4-(9,10-dioxo-4-(phenylamino)-5,8,9,10-tetrahydroa...)
Affinity DataIC50: 5.50E+3nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326561BDBM50326561(2-(2,3-dihydro-1H-pyrrolo[3,4-b]quinolin-3-yl)acet...)
Affinity DataIC50: 5.50E+3nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50118752BDBM50118752(6-(3,3-Diphenyl-propyl)-2-(oxalyl-amino)-4,5,6,7-t...)
Affinity DataKi:  5.80E+3nMpH: 7.0Assay Description:Inhibitory effect against T cell protein tyrosine phosphatase (TC-PTP) using p-nitrophenyl phosphate as substrate at pH 7.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326557BDBM50326557(NSC45576, 2 | CHEMBL1253920 | (E)-5-((2-hydroxynap...)
Affinity DataIC50: 8.10E+3nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326561BDBM50326561(2-(2,3-dihydro-1H-pyrrolo[3,4-b]quinolin-3-yl)acet...)
Affinity DataIC50: 8.10E+3nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425808BDBM50425808(CHEMBL2316906)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PTPalpha (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607111BDBM50607111(CHEMBL5218807)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PTPalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425806BDBM50425806(CHEMBL2316907)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PTPalpha (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425807BDBM50425807(CHEMBL2316902)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PTPalpha (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326560BDBM50326560(2-amino-3-(5-oxo-5H-benzo[a]phenoxazin-10-yl)propa...)
Affinity DataIC50: 1.30E+4nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079855BDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50: 1.30E+4nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1 alpha (LRP) (human PTPases.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135663BDBM50135663(3-(4-Biphenyl-4-ylmethyl-piperazin-1-ylmethyl)-pyr...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro inhibitory concentration required against Protein-tyrosine phosphatase alpha in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079856BDBM50079856([2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thio...)
Affinity DataIC50: 1.70E+4nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1 alpha (LRP) (human PTPases.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135668BDBM50135668(3-(4-Benzyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50: 2.40E+4nMAssay Description:In vitro inhibitory concentration required against Protein-tyrosine phosphatase alpha in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135673BDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50: 2.80E+4nMAssay Description:In vitro inhibitory concentration required against Protein-tyrosine phosphatase alpha in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50409191BDBM50409191(CHEMBL365490)
Affinity DataIC50: 3.37E+4nMAssay Description:Inhibition of PTPalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326558BDBM50326558(10,13-dimethyl-17-(2-(6-thioxo-3H-purin-9(6H)-yl)a...)
Affinity DataIC50: 3.50E+4nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222205BDBM50222205((1S,2R,4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-10,...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246580BDBM50246580((S)-2-((4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-hyd...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194130BDBM50194130(Oleanolic acid 3-O-(3',3'-dimethyl)succinate | 3-O...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246744BDBM50246744((4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(4-carboxy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246620BDBM50246620(3-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246621BDBM50246621(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246745BDBM50246745(3-(4-Carboxy-benzyloxy)-28-[4-butyric ((S)-1-carbo...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079577BDBM50079577((4aS,6aS,6bR,10S,12aR,14bS)-10-Hydroxy-2,2,6a,6b,9...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148911BDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246653BDBM50246653((S)-2-(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246668BDBM50246668(3-(benzo[d][1,3]dioxol-5-yl)-2-(5-((4aR,6aS,6bR,8a...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PTPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343147BDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PTPalpha expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308158BDBM50308158(3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3...)
Affinity DataIC50: 5.00E+4nMpH: 7.0Assay Description:Inhibition of PTPalpha expressed in Escherichia coli assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH 7 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343142BDBM50343142(N-(4-butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PTPalpha expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343148BDBM50343148(N1-(1-(4-(4-fluorophenyl)piperazin-1-yl)-1-(thioph...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PTPalpha expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112357BDBM50112357(CHEMBL3609375)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPalpha using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
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