Compile Data Set for Download or QSAR
Report error Found 5590 for UniProtKB: P18507
LigandPNGBDBM26263(ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricycl...)
Affinity DatapH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26263(ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricycl...)
Affinity DataT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26263(ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricycl...)
Affinity DataT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM540734(US11261211, Compound SA-1)
Affinity DataEC50:  750nMAssay Description:This assay is not specified.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

LigandPNGBDBM540735(US11261211, Compound SA-2)
Affinity DataEC50:  750nMAssay Description:This assay is not specified.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

LigandPNGBDBM540736(US11261211, Compound SA-4)
Affinity DataEC50:  1.50E+3nMAssay Description:This assay is not specified.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

LigandPNGBDBM540737(US11261211, Compound SA-3)
Affinity DataEC50:  1.50E+3nMAssay Description:This assay is not specified.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

LigandPNGBDBM540739(US11261211, Compound SA-8)
Affinity DataEC50:  1.50E+3nMAssay Description:This assay is not specified.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

LigandPNGBDBM540741(US11261211, Compound SA-5)
Affinity DataEC50:  1.50E+3nMAssay Description:This assay is not specified.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

LigandPNGBDBM655561(US11912737, Example 1 | US11912737, Example 7.)
Affinity DataEC50:  1.50E+3nMAssay Description:Whole cell currents were measured with HEKA EPC-10 amplifiers using PatchMaster software or by using the high throughput QPatch platform (Sophion). B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

LigandPNGBDBM655564(US11912737, Example 2 | US11912737, Example 10.)
Affinity DataEC50:  1.50E+3nMAssay Description:Whole cell currents were measured with HEKA EPC-10 amplifiers using PatchMaster software or by using the high throughput QPatch platform (Sophion). B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

LigandPNGBDBM655565(US11912737, Example 3 | US11912737, Example 11.)
Affinity DataEC50: >2.00E+3nMAssay Description:Whole cell currents were measured with HEKA EPC-10 amplifiers using PatchMaster software or by using the high throughput QPatch platform (Sophion). B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

LigandPNGBDBM669517(US20240132445, Compound Control 3)
Affinity DataEC50:  1.04E+4nMAssay Description:A whole-cell patch-clamp technique was used to study the allosteric regulation effect of the compound of the present invention on the GABAA (α1&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandPNGBDBM669518(US20240132445, Compound 20)
Affinity DataEC50:  1.56E+3nMAssay Description:A whole-cell patch-clamp technique was used to study the allosteric regulation effect of the compound of the present invention on the GABAA (α1&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandPNGBDBM50191342(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)
Affinity DataEC50:  237nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50258228(CHEMBL4078922)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258239(CHEMBL4091891)
Affinity DataEC50:  1.16E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258255(CHEMBL4062424)
Affinity DataEC50:  1.64E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258256(CHEMBL3427532)
Affinity DataEC50:  125nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258216(CHEMBL4105630)
Affinity DataEC50:  375nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258229(CHEMBL4103751)
Affinity DataEC50:  1.05E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258248(CHEMBL4084134)
Affinity DataEC50: >3.00E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258249(CHEMBL4080678)
Affinity DataEC50:  1.60E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258244(CHEMBL4100583)
Affinity DataEC50: >3.00E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258254(CHEMBL4073780)
Affinity DataEC50:  225nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258252(CHEMBL4073679)
Affinity DataEC50:  291nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258243(CHEMBL4081622)
Affinity DataEC50:  1.76E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258217(CHEMBL3427530)
Affinity DataEC50:  979nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258218(CHEMBL4103198)
Affinity DataEC50: >3.65E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258250(CHEMBL4104908)
Affinity DataEC50: >3.00E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258251(CHEMBL4072311)
Affinity DataEC50: >3.00E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258242(CHEMBL4071062)
Affinity DataEC50: >3.00E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
LigandPNGBDBM50258253(CHEMBL4085062)
Affinity DataEC50:  1.50E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25883(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)
Affinity DataEC50:  146nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259820(CHEMBL4098713)
Affinity DataEC50:  5.15E+3nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259821(CHEMBL2332214)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259815(CHEMBL4090978)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259820(CHEMBL4098713)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259822(CHEMBL514974)
Affinity DataEC50:  29nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259824(CHEMBL475022)
Affinity DataEC50:  844nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25883(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259821(CHEMBL2332214)
Affinity DataEC50:  470nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259824(CHEMBL475022)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259824(CHEMBL475022)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259822(CHEMBL514974)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259814(CHEMBL4062225)
Affinity DataEC50:  118nMAssay Description:Modulation of recombinant human GABA alpha2beta3gamma2 receptor expressed in HEK293 cells assessed as change in GABA-induced current at -80 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259815(CHEMBL4090978)
Affinity DataEC50:  321nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259816(CHEMBL4063081)
Affinity DataEC50:  3.02E+3nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259825(CHEMBL4089504)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50259816(CHEMBL4063081)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Displayed 1 to 50 (of 5590 total ) | Next | Last >>
Jump to: