Compile Data Set for Download or QSAR
Report error Found 5736 for UniProtKB: P27986
LigandChemical structure of BindingDB Monomer ID 50573157BDBM50573157(CHEMBL4850297)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged full length P110delta/full length untagged human p85alpha expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50573166BDBM50573166(CHEMBL4869783)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged full length P110delta/full length untagged human p85alpha expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50573177BDBM50573177(CHEMBL4167702)
Affinity DataKi:  0.0126nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged full length P110delta/full length untagged human p85alpha expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50573167BDBM50573167(CHEMBL4858875)
Affinity DataKi:  0.0158nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged full length P110delta/full length untagged human p85alpha expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149477BDBM50149477(CHEMBL3770993 | US8242104, Compound 375 | US108510...)
Affinity DataKi:  0.0160nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340389BDBM340389(US9758538, Example 77)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340459BDBM340459(US9758538, Example 149)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340319BDBM340319(US9758538, Example 9 | US9758538, Example 8 | US97...)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340384BDBM340384(US9758538, Example 72)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340317BDBM340317(US9758538, Example 5)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340449BDBM340449(US9758538, Example 139)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340450BDBM340450(US9758538, Example 140)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340405BDBM340405(US9758538, Example 93)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340348BDBM340348(US9758538, Example 36)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340409BDBM340409(US9758538, Example 97)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340336BDBM340336(US9758538, Example 24)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340464BDBM340464(US9758538, Example 154)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340404BDBM340404(US9758538, Example 92)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340401BDBM340401(US9758538, Example 89)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340337BDBM340337(US9758538, Example 26 | US9758538, Example 27 | US...)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340402BDBM340402(US9758538, Example 90)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340423BDBM340423(US9758538, Example 111)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340336BDBM340336(US9758538, Example 24)
Affinity DataKi: <0.0180nMAssay Description:Inhibition of recombinant human full-length PI3K p110alpha/p85alpha (322 to 600) expressed in baculovirus infected Sf21 cells using phosphatidylinosi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 340358BDBM340358(US9758538, Example 46)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340428BDBM340428(US9758538, Example 117)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 207378BDBM207378(US9260439, 262)
Affinity DataKi: <0.0180nMAssay Description:Inhibition of recombinant human full-length PI3K p110alpha/p85alpha (322 to 600) expressed in baculovirus infected Sf21 cells using phosphatidylinosi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 340426BDBM340426(US9758538, Example 114)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 207196BDBM207196(US9260439, 173)
Affinity DataKi: <0.0180nMAssay Description:Inhibition of recombinant human full-length PI3K p110alpha/p85alpha (322 to 600) expressed in baculovirus infected Sf21 cells using phosphatidylinosi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 340350BDBM340350(US9758538, Example 38)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340414BDBM340414(US9758538, Example 102)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 207217BDBM207217(US9260439, 238 | US9260439, 239 | US9260439, 194)
Affinity DataKi: <0.0180nMAssay Description:Inhibition of recombinant human full-length PI3K p110alpha/p85alpha (322 to 600) expressed in baculovirus infected Sf21 cells using phosphatidylinosi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 340376BDBM340376(US9758538, Example 64)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340377BDBM340377(US9758538, Example 65)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340314BDBM340314(US9758538, Example 2 | (Scheme A): Preparation of ...)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340431BDBM340431(US9758538, Example 120)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340368BDBM340368(US9758538, Example 56)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340429BDBM340429(US9758538, Example 118)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340430BDBM340430(US9758538, Example 119)
Affinity DataKi: <0.0180nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 340314BDBM340314(US9758538, Example 2 | (Scheme A): Preparation of ...)
Affinity DataKi: <0.0180nMAssay Description:Inhibition of recombinant human full-length PI3K p110alpha/p85alpha (322 to 600) expressed in baculovirus infected Sf21 cells using phosphatidylinosi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 340384BDBM340384(US9758538, Example 72)
Affinity DataKi: <0.0180nMAssay Description:Inhibition of recombinant human full-length PI3K p110alpha/p85alpha (322 to 600) expressed in baculovirus infected Sf21 cells using phosphatidylinosi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 340346BDBM340346(US9758538, Example 34)
Affinity DataKi:  0.0190nMAssay Description:Inhibition of recombinant human full-length PI3K p110alpha/p85alpha (322 to 600) expressed in baculovirus infected Sf21 cells using phosphatidylinosi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 340346BDBM340346(US9758538, Example 34)
Affinity DataKi:  0.0190nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50145416BDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.0190nMAssay Description:Competitive inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate preincubated for 10 mins followed by ATP addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 414902BDBM414902(US10435414, Compound 171 | (S)-2-((1-(2- aminobenz...)
Affinity DataKi: <0.0200nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 272989BDBM272989((2R,3S)-1-(1-(2- aminobenzo[d]oxazol- 5-yl)-7,8,9,...)
Affinity DataKi: <0.0200nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 272991BDBM272991((S)-2-((1-(5-(1H-1,2,4- triazol-5-yl)pyridin-2- yl...)
Affinity DataKi: <0.0200nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 272984BDBM272984((S)-2-((1-(2-amino-7- fluorobenzo[d]oxazol- 5-yl)-...)
Affinity DataKi: <0.0200nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 272949BDBM272949((S)-2-((1-(2- aminobenzo[d]oxazol- 5-yl)-7,8,9,10-...)
Affinity DataKi: <0.0200nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 272944BDBM272944((S)-2-((1-(2-amino-7- fluorobenzo[d]oxazol- 5-yl)-...)
Affinity DataKi: <0.0200nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 272945BDBM272945((S)-1-(1-(2- aminobenzo[d]oxazol- 5-yl)-7,8,9,10- ...)
Affinity DataKi: <0.0200nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

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