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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataKd:  400nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataKd:  74nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataKd:  120nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataKd:  46nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM319787(US10174013, Example 2A | 5,6-dibromo-4-nitro-2-(pi...)
Affinity DataKd:  130nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM319787(US10174013, Example 2A | 5,6-dibromo-4-nitro-2-(pi...)
Affinity DataKd:  18nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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LigandPNGBDBM319787(US10174013, Example 2A | 5,6-dibromo-4-nitro-2-(pi...)
Affinity DataKd:  28nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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LigandPNGBDBM319787(US10174013, Example 2A | 5,6-dibromo-4-nitro-2-(pi...)
Affinity DataKd:  15nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331627(US9725465, Example 1 | Preparation of 2-(4-(6,7-di...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331628(US9725465, Example 2 | Preparation of 2-(4-(7-meth...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331629(US9725465, Example 3 | Preparation of 2-(4-(5H-pyr...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331630(US9725465, Example 4 | Preparation of 2-(4-(6,7-di...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331631(US9725465, Example 5 | Preparation of 2-(4-(6,7-di...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331632(US9725465, Example 6 | Preparation of N-(5-(tert-b...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331633(US9725465, Example 7 | Preparation of 2-(4-(3-amin...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331634(US9725465, Example 8 | Preparation of 2-(4-(6,7-di...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331635(US9725465, Example 9 | Preparation of 2-(4-(5-meth...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331636(US9725465, Example 10 | Preparation of 2-(4-(thien...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331637(US9725465, Example 11 | Preparation of 2-(4-(1,5-n...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331638(US9725465, Example 12 | Preparation of 2-(4-(1,6-n...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331639(US9725465, Example 13 | Preparation of 2-(4-(5,7-d...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331640(US9725465, Example 14 | Preparation of 2-(4-(1H-im...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331643(US9725465, Example 46 | Preparation of 2-(4-(6,7-d...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331644(US9725465, Example 62 | Preparation of N-(5-(tert-...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331645(US9725465, Example 63 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331646(US9725465, Example 64 | Preparation of 5-(4-(2-((5...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331647(US9725465, Example 65 | Preparation of 5-(4-(2-((5...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331648(US9725465, Example 66 | Preparation of 5-(4-(2-((5...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331649(US9725465, Example 67 | Preparation of 5-(4-(2-((5...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331650(US9725465, Example 68 | Preparation of 5-(4-(2-((5...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331651(US9725465, Example 69 | Preparation of 5-(4-(2-((5...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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US Patent
LigandPNGBDBM331652(US9725465, Example 70 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331653(US9725465, Example 74 | Preparation of ((2-(3-fluo...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331654(US9725465, Example 75 | Preparation of 2-(4-(6,7-b...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331655(US9725465, Example 76 | Preparation of 2-(4-(2,3-d...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331656(US9725465, Example 77 | 2-(2-fluoro-4-(6-methoxy-7...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331656(US9725465, Example 77 | 2-(2-fluoro-4-(6-methoxy-7...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331657(US9725465, Example 78 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331658(US9725465, Example 79 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331658(US9725465, Example 79 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331659(US9725465, Example 80 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331660(US9725465, Example 81 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331661(US9725465, Example 82 | Preparation of 2-(4-(6-(2-...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331662(US9725465, Example 83 | Preparation of 2-(4-(6-bro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331663(US9725465, Example 84 | Preparation of 2-(4-(6-(2,...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331664(US9725465, Example 85 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331665(US9725465, Example 86 | Preparation of 2-(4-(7-eth...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331666(US9725465, Example 87 | Preparation of 2-(2-Fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331667(US9725465, Example 88 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
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LigandPNGBDBM331668(US9725465, Example 89 | Preparation of 2-(4-(6-(az...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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