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Report error Found 21 of affinity data for UniProtKB/TrEMBL: P42677
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420401(CHEMBL2089255 | US11208696, Example 31)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50343559(1-(2-HYDROXYETHYL)-8-[[5-(4-METHYLPIPERAZIN-1-YL)-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MPS1 (unknown origin) in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420400(CHEMBL2089254)
Affinity DataIC50: 37nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420401(CHEMBL2089255 | US11208696, Example 31)
Affinity DataIC50: 131nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420399(CHEMBL2089253)
Affinity DataIC50: 228nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  470nMAssay Description:Binding affinity to human RPS27 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15912(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 529nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15913(4-amino-5-cyano-6-ethoxy-N-[(4-methanesulfonylphen...)
Affinity DataIC50: 568nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420400(CHEMBL2089254)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420398(CHEMBL2089252)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15926(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-phenyla...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  7.65E+3nMAssay Description:Binding affinity to human RPS27 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50361088(CHEMBL1933582)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPS1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50361089(CHEMBL1933576)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPS1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50048374(CHEMBL3310151)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50048362(CHEMBL3309995)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50048357(CHEMBL3309990)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021626(CHEMBL3298400)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50048365(CHEMBL3309998)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021618(CHEMBL3297762 | US9145418, 2)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50048364(CHEMBL3309997)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed