Compile Data Set for Download or QSAR
Report error Found 683 for UniProtKB: P55210
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10652BDBM10652((3S)-3-[(2S)-2-[(4S)-4-[(3S)-3-acetamido-3-formami...)
Affinity DataIC50: 0.00800nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160960BDBM50160960((S)-3-{(S)-2-[3-((S)-2-Acetylamino-3-carboxy-propi...)
Affinity DataIC50: 0.0100nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160974BDBM50160974([3-(2-{5-tert-Butyl-3-[(4-methyl-furazan-3-ylmethy...)
Affinity DataIC50: 0.0130nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160987BDBM50160987((S)-3-(2-{5-tert-Butyl-3-[(4-methyl-furazan-3-ylme...)
Affinity DataIC50: 0.0360nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160989BDBM50160989((S)-3-(2-{5-tert-Butyl-3-[(4-methyl-furazan-3-ylme...)
Affinity DataIC50: 0.0420nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160959BDBM50160959((S)-5-{[(Hexyl-methyl-amino)-methyl]-amino}-3-(2-{...)
Affinity DataIC50: 0.0650nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160954BDBM50160954((S)-5-[(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-ami...)
Affinity DataIC50: 0.0830nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160969BDBM50160969((S)-3-(2-{5-(1-Ethyl-1-methyl-propyl)-3-[(4-methyl...)
Affinity DataIC50: 0.0870nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160957BDBM50160957([3-(2-{5-tert-Butyl-3-[(4-methyl-furazan-3-ylmethy...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160970BDBM50160970((S)-3-(2-{3-[(4-Methyl-furazan-3-ylmethyl)-amino]-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160981BDBM50160981((S)-3-(2-{3-[(4-Methyl-furazan-3-ylmethyl)-amino]-...)
Affinity DataIC50: 0.110nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160961BDBM50160961((S)-5-Benzylsulfanyl-3-{(S)-2-[2-(5-methanesulfony...)
Affinity DataIC50: 0.120nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160977BDBM50160977((S)-5-[(1,3-Dihydro-isoindol-2-ylmethyl)-amino]-3-...)
Affinity DataIC50: 0.130nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160971BDBM50160971((S)-5-{[(Butyl-methyl-amino)-methyl]-amino}-3-(2-{...)
Affinity DataIC50: 0.130nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160946BDBM50160946((S)-3-(2-{5-tert-Butyl-3-[(4-methyl-furazan-3-ylme...)
Affinity DataIC50: 0.130nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160950BDBM50160950((S)-5-{[(Hexyl-methyl-amino)-methyl]-amino}-3-(2-{...)
Affinity DataIC50: 0.140nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160976BDBM50160976((3S)-3-(2-(5-tert-butyl-3-((4-methyl-1,2,5-oxadiaz...)
Affinity DataIC50: 0.140nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160985BDBM50160985((S)-5-[(7-Aza-bicyclo[2.2.1]hept-7-ylmethyl)-amino...)
Affinity DataIC50: 0.260nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160967BDBM50160967((S)-5-(Dimethylaminomethyl-amino)-3-(2-{3-[(4-meth...)
Affinity DataIC50: 0.310nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160991BDBM50160991((S)-3-(2-{3-[(4-Methyl-furazan-3-ylmethyl)-amino]-...)
Affinity DataIC50: 0.320nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160956BDBM50160956((S)-3-(2-{3-[(4-Methyl-furazan-3-ylmethyl)-amino]-...)
Affinity DataIC50: 0.410nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160955BDBM50160955((S)-3-(2-{5-tert-Butyl-3-[(4-methyl-furazan-3-ylme...)
Affinity DataIC50: 0.480nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160973BDBM50160973((S)-5-Benzylsulfanyl-4-oxo-3-(2-{2-oxo-3-[(thiazol...)
Affinity DataIC50: 0.490nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160979BDBM50160979((S)-3-(2-{5-tert-Butyl-3-[(4-methyl-furazan-3-ylme...)
Affinity DataIC50: 0.540nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160944BDBM50160944((S)-5-{[(Ethyl-methyl-amino)-methyl]-amino}-3-(2-{...)
Affinity DataIC50: 0.540nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160962BDBM50160962((S)-3-(2-{5-Ethyl-3-[(4-methyl-furazan-3-ylmethyl)...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258696BDBM50258696((S)-1-[4-(Allyloxy)benzyl]-5-[1-(2-methoxymethylpy...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160947BDBM50160947((S)-5-Benzylsulfanyl-3-(2-{3-[(4-methyl-furazan-3-...)
Affinity DataIC50: 0.730nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160943BDBM50160943((S)-3-(2-{3-[(4-Methyl-furazan-3-ylmethyl)-amino]-...)
Affinity DataIC50: 0.75nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160949BDBM50160949((S)-5-Benzylsulfanyl-4-oxo-3-(2-{2-oxo-3-[(thiophe...)
Affinity DataIC50: 0.810nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160951BDBM50160951((S)-5-[(4-Benzyl-piperidin-1-ylmethyl)-amino]-3-(2...)
Affinity DataIC50: 0.840nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434076BDBM50434076(CHEMBL2381343)
Affinity DataIC50: 0.951nMAssay Description:Inhibition of human recombinant caspase-7 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160964BDBM50160964((S)-3-(2-{3-[(4-Methyl-furazan-3-ylmethyl)-amino]-...)
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160978BDBM50160978((S)-5-{[(Ethoxymethyl-methyl-amino)-methyl]-amino}...)
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160965BDBM50160965((S)-3-(2-{3-[(4-Methyl-furazan-3-ylmethyl)-amino]-...)
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160948BDBM50160948((S)-5-Benzylsulfanyl-4-oxo-3-(2-{2-oxo-3-[(thiazol...)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200306BDBM50200306((S)-1-(4-iodobenzyl)-5-[1-(2-methoxymethylpyrrolid...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of caspase 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258379BDBM50258379((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273338BDBM50273338((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataEC50:  2.20nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273991BDBM50273991((S)-1-(4-Fluorobenzyl)-5-(2-(pyrimidin-4-yloxymeth...)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258381BDBM50258381((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160986BDBM50160986((S)-5-Benzylsulfanyl-3-{2-[3-(2-methyl-benzothiazo...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160972BDBM50160972((S)-5-Benzylsulfanyl-3-(2-{3-[(3-methyl-isoxazol-5...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160983BDBM50160983((S)-5-Benzylsulfanyl-3-(2-{3-[3-(3-methyl-[1,2,4]o...)
Affinity DataIC50: 2.60nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10246BDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10246BDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 2.95nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160952BDBM50160952((S)-5-(Diethylaminomethyl-amino)-3-(2-{3-[(4-methy...)
Affinity DataIC50: 3.20nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031602BDBM50031602(CHEMBL3359194)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160982BDBM50160982((S)-5-Benzylsulfanyl-3-(2-{3-[(2,3-dihydro-benzo[1...)
Affinity DataIC50: 3.30nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340543BDBM50340543((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
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