Compile Data Set for Download or QSAR
Report error Found 53 of affinity data for UniProtKB/TrEMBL: P9WNX1
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650594(CHEMBL5629885)
Affinity DataKd:  17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650593(CHEMBL5081820)
Affinity DataKd:  640nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50608610(CHEMBL5279457)
Affinity DataIC50: 0.960nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50608612(CHEMBL1904209)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR using dihydrofolate as substrate preincubated for 1 min followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50290152(CHEMBL526013)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli assessed as reduction in consumption of NADPH using DHF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR using 45 uM DHF as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM66082(SMR000449324 | MLS001401431 | (2S)-2-[[4-[[2,4-bis...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50134784(CHEMBL526243 | TCMDC-137820)
Affinity DataIC50: 10nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli assessed as reduction in consumption of NADPH using DHF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50608609(TCMDC-124259 | CHEMBL586115)
Affinity DataIC50: 22nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50290154(CHEMBL3245817)
Affinity DataIC50: 30nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM66082(SMR000449324 | MLS001401431 | (2S)-2-[[4-[[2,4-bis...)
Affinity DataIC50: 35nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50290153(CHEMBL3245816)
Affinity DataIC50: 50nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50290151(CHEMBL531405 | TCMDC-132109)
Affinity DataIC50: 55nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli assessed as reduction in consumption of NADPH using DHF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM210930(UCP1173)
Affinity DataIC50: 177nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM210931(UCP1175)
Affinity DataIC50: 460nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50290150(CHEMBL4160822)
Affinity DataIC50: 820nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50290149(CHEMBL4174883)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50257636(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50290155(CHEMBL4169358)
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR assessed as reduction in consumption of NADPH using DHF as substrate incubated for 3 mins measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50290156(CHEMBL4162075)
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR assessed as reduction in consumption of NADPH using DHF as substrate incubated for 3 mins measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50290173(CHEMBL4160241)
Affinity DataIC50: 5.82E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50537326(CHEMBL4544311)
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544190(CHEMBL4642912)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544189(CHEMBL4638488)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50608611(CHEMBL4436643)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50516935(CHEMBL4526073)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50138163(CHEMBL3752202)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR using 45 uM DHF as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544187(CHEMBL4633659)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544193(CHEMBL1540399)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544183(CHEMBL4647549)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544188(CHEMBL4643280)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50119764(CHEMBL3616528)
Affinity DataIC50: 3.86E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50537327(CHEMBL4578986)
Affinity DataIC50: 4.31E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50019166(CHEMBL336718)
Affinity DataIC50: 4.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50019166(CHEMBL336718)
Affinity DataIC50: 4.91E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544184(CHEMBL4638799)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544195(CHEMBL4639355)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50290157(CHEMBL4171895)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM38964(cid_3238641 | MLS000085462 | SMR000020397 | 3-[(4-...)
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544191(CHEMBL4635914)
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50516935(CHEMBL4526073)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544186(CHEMBL4638822)
Affinity DataIC50: 1.52E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544192(CHEMBL4644947)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544182(CHEMBL4649874)
Affinity DataIC50: 2.42E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50508821(CHEMBL4443020)
Affinity DataIC50: 4.42E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544194(CHEMBL4634216)
Affinity DataIC50: 4.54E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544196(CHEMBL4637819)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50544185(CHEMBL4638943)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
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