Compile Data Set for Download or QSAR
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Found 686 for UniProtKB: Q00961
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015743(Acetic acid 3-[1-(3,6-dihydro-2H-pyridin-1-yl)-cyc...)
Affinity DataKi:  6nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015738(3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-phe...)
Affinity DataKi:  7nMAssay Description:Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50111396(CHEMBL273636 | [[(S)-1-(4-Bromo-phenyl)-ethylamino...)
Affinity DataKi:  11.6nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015734(1-(1-Thiophen-2-yl-cyclohexyl)-1,2,3,6-tetrahydro-...)
Affinity DataKi:  12nMAssay Description:Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015741(1-[1-(3-Methoxy-phenyl)-cyclohexyl]-1,2,3,6-tetrah...)
Affinity DataKi:  33nMAssay Description:Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015732(1-(1-Phenyl-cyclohexyl)-1,2,3,6-tetrahydro-pyridin...)
Affinity DataKi:  37nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015733(3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-ben...)
Affinity DataKi:  56nMAssay Description:Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataKi:  60nMAssay Description:Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50419775(CHEMBL1950808)
Affinity DataKi:  70nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015735(1-(1-m-Tolyl-cyclohexyl)-1,2,3,6-tetrahydro-pyridi...)
Affinity DataKi:  81nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataKi:  91nMAssay Description:Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015744(1-[1-(3-Methoxymethoxy-phenyl)-cyclohexyl]-1,2,3,6...)
Affinity DataKi:  92nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164540((2R,3S)-1-(Phenanthrene-2-carbonyl)-piperazine-2,3...)
Affinity DataKi:  96nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164549((2R,3S)-1-(7-Bromo-phenanthrene-2-carbonyl)-pipera...)
Affinity DataKi:  99.4nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164549((2R,3S)-1-(7-Bromo-phenanthrene-2-carbonyl)-pipera...)
Affinity DataKi:  100nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015740(1-[1-(3-Vinyl-phenyl)-cyclohexyl]-1,2,3,6-tetrahyd...)
Affinity DataKi:  114nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50018933(1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine | CHEM...)
Affinity DataKi:  170nMAssay Description:Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015731(1-[1-(3-Methylsulfanyl-phenyl)-cyclohexyl]-1,2,3,6...)
Affinity DataKi:  231nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015736(1-[1-(3-Fluoro-phenyl)-cyclohexyl]-1,2,3,6-tetrahy...)
Affinity DataKi:  281nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164555((2R,3S)-1-(9,10-Dihydro-phenanthrene-2-carbonyl)-p...)
Affinity DataKi:  290nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164555((2R,3S)-1-(9,10-Dihydro-phenanthrene-2-carbonyl)-p...)
Affinity DataKi:  290nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015739(3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-ben...)
Affinity DataKi:  324nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50368882(CHEMBL147585 | SK&F-10047 | SK-10047)
Affinity DataKi:  370nMAssay Description:Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50368882(CHEMBL147585 | SK&F-10047 | SK-10047)
Affinity DataKi:  370nMAssay Description:Binding affinity of compound was tested on Phencyclidine binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015730(1-[1-(3-Trifluoromethyl-phenyl)-cyclohexyl]-1,2,3,...)
Affinity DataKi:  422nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataKi:  530nMAssay Description:Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015742(1-[1-(3-[1,3]Dioxolan-2-yl-phenyl)-cyclohexyl]-1,2...)
Affinity DataKi:  601nMAssay Description:Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50050704((R)-4-(3-Phosphono-propyl)-piperazine-2-carboxylic...)
Affinity DataKi:  630nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50405724(CHEMBL1169565)
Affinity DataKi:  630nMAssay Description:Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50038169((3R,4R)-3-Amino-1-hydroxy-4-methyl-pyrrolidin-2-on...)
Affinity DataKi:  650nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164548((2R,3S)-1-(7-Bromo-9,10-dihydro-phenanthrene-2-car...)
Affinity DataKi:  660nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164548((2R,3S)-1-(7-Bromo-9,10-dihydro-phenanthrene-2-car...)
Affinity DataKi:  660nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50405723(CHEMBL1169564)
Affinity DataKi:  680nMAssay Description:Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50062599(3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN3...)
Affinity DataKi:  700nMAssay Description:Compound with the N-methyl-D-aspartate glutamate receptor blocking activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015745(1-[1-(3-Benzyloxy-phenyl)-cyclohexyl]-1,2,3,6-tetr...)
Affinity DataKi:  733nMAssay Description:Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50038175((3R,4R)-3-Amino-1,4-dihydroxy-pyrrolidin-2-one | C...)
Affinity DataKi:  750nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
University Of Copenhagen

LigandPNGBDBM213888(1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]-quinox...)
Affinity DataKi: >800nM ΔG°: >-34.8kJ/mole IC50: >3.00E+3nMpH: 7.4 T: 2°CAssay Description:Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50018932(1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine | CHEM...)
Affinity DataKi:  820nMAssay Description:Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164556((2R,3S)-1-((E)-3-Naphthalen-2-yl-acryloyl)-piperaz...)
Affinity DataKi:  850nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164546((2R,3S)-1-(9H-Fluorene-2-carbonyl)-piperazine-2,3-...)
Affinity DataKi:  1.17E+3nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50288367(3-(2,3-Dioxo-7-pyrrol-1-yl-6-trifluoromethyl-3,4-d...)
Affinity DataKi:  1.20E+3nMAssay Description:Compound was tested for binding affinity against glycine site of NMDA receptor using [3H]-glycine as a radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50004897((APV)2-Amino-5-phosphono-pentanoic acid | (R)-2-Am...)
Affinity DataKi:  1.64E+3nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50419786(CHEMBL1950795)
Affinity DataKi:  1.80E+3nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50364074(CHEMBL1950805)
Affinity DataKi:  1.90E+3nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50419787(CHEMBL1950794)
Affinity DataKi:  2.10E+3nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50048875(CHEMBL431343 | N-[3-(5-Methoxy-1,2,3,4-tetrahydro-...)
Affinity DataKi:  2.13E+3nMAssay Description:Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50018929(3-Methyl-1-(1-phenyl-cyclohexyl)-piperidine | CHEM...)
Affinity DataKi:  2.15E+3nMAssay Description:Inhibition activity against binding of phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50018929(3-Methyl-1-(1-phenyl-cyclohexyl)-piperidine | CHEM...)
Affinity DataKi:  2.15E+3nMAssay Description:Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50038159((R)-3-Amino-1-hydroxy-pyrrolidin-2-one | CHEMBL335...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50405723(CHEMBL1169564)
Affinity DataKi:  2.60E+3nMAssay Description:Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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