TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.04E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1alpha/GluN2C receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]-GABA release at NMDA receptor.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.40E+5nMAssay Description:Compound was evaluated for in vitro inhibition of cortical slice at NMDA receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.81E+4nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]TCP at NMDA receptor.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 9.00E+4nMAssay Description:Agonist activity at recombinant rat GluN1a/GluN2C expressed in Xenopus laevis oocytes at -40 mV holding potential in presence of glutamate by two-ele...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.13E+5nMAssay Description:Positive allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced curren...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 3.72E+4nMAssay Description:Positive allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced curren...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 3.62E+4nMAssay Description:Positive allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced curren...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 2.61E+4nMAssay Description:Positive allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced curren...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 2.24E+4nMAssay Description:Positive allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced curren...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 5.01E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 5.01E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.26E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 398nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 398nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.59E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 398nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 6.31E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 7.94E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: <3.16E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 2.51E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 3.98E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 3.98E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 5.01E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.26E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 5.01E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 6.31E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 2.51E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: <3.16E+4nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 6.31E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.59E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.26E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 3.16E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 794nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.26E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 3.16E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 36nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 63nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 74nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 190nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Physiology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair

















































