Compile Data Set for Download or QSAR
Report error Found 67 of affinity data for UniProtKB/TrEMBL: Q02224
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533247(CHEMBL4470356)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533247(CHEMBL4470356)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533251(CHEMBL4579540)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533251(CHEMBL4579540)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533246(CHEMBL4549646)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533246(CHEMBL4549646)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533249(CHEMBL4468555)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533249(CHEMBL4468555)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533248(CHEMBL4515745)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533248(CHEMBL4515745)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataKi:  3.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50653004(CHEMBL5712053)
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50653003(CHEMBL5712065)
Affinity DataKi:  4.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50653004(CHEMBL5712053)
Affinity DataKi:  4.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50653004(CHEMBL5712053)
Affinity DataKi:  4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataKi:  12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533245(CHEMBL4579162)
Affinity DataIC50: 14nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533245(CHEMBL4579162)
Affinity DataIC50: 14nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533244(CHEMBL4466617)
Affinity DataIC50: 19nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533244(CHEMBL4466617)
Affinity DataIC50: 19nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533250(CHEMBL4483703)
Affinity DataIC50: 24nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533250(CHEMBL4483703)
Affinity DataIC50: 24nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438555(CHEMBL2413142)
Affinity DataIC50: 32nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438554(CHEMBL2413143)
Affinity DataIC50: 35nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533249(CHEMBL4468555)
Affinity DataEC50:  39nMAssay Description:Inhibition of CENP-E in human HeLa cells assessed as HH3 phosphorylated levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533249(CHEMBL4468555)
Affinity DataEC50:  39nMAssay Description:Inhibition of CENP-E in human HeLa cells assessed as HH3 phosphorylated levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438549(CHEMBL2413146)
Affinity DataIC50: 50nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 56nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataKi:  61nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataKi:  64nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438562(CHEMBL2413135)
Affinity DataIC50: 72nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50653003(CHEMBL5712065)
Affinity DataKi:  73nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533248(CHEMBL4515745)
Affinity DataEC50:  79nMAssay Description:Inhibition of CENP-E in human HeLa cells assessed as HH3 phosphorylated levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533248(CHEMBL4515745)
Affinity DataEC50:  79nMAssay Description:Inhibition of CENP-E in human HeLa cells assessed as HH3 phosphorylated levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438560(CHEMBL2413137)
Affinity DataIC50: 100nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 134nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438553(CHEMBL2413144)
Affinity DataIC50: 140nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 283nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438561(CHEMBL2413136)
Affinity DataIC50: 300nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438556(CHEMBL2413141)
Affinity DataIC50: 370nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438552(CHEMBL2413145)
Affinity DataIC50: 540nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
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