Compile Data Set for Download or QSAR
maximum 50k data
Found 210 of affinity data for UniProtKB/TrEMBL: Q13002
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM85740(Dysiherbaine)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]kianic acid from recombinant GluK2 kainate receptor (unknown origin) expressed in HEK293 cell membranes measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50031704((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...)
Affinity DataKi:  10nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053058((4E,6E)-(R)-7-[4,5-Bis-(1-hydroxy-vinyl)-pyrrolidi...)
Affinity DataKi:  18.3nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053067((2S,3S,4S)-3-Carboxymethyl-4-(1-phenyl-vinyl)-pyrr...)
Affinity DataKi:  29.8nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053061((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-chloro-phenyl)-...)
Affinity DataKi:  31.7nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  32nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 2 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  32nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053087((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-fluoro-phenyl)-...)
Affinity DataKi:  38.4nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053088((2S,3S,4S)-3-Carboxymethyl-4-(1-p-tolyl-vinyl)-pyr...)
Affinity DataKi:  41.1nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088216(CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...)
Affinity DataKi:  48nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50200526(CHEMBL1234118)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-kainate from human recombinant GluK2 receptor expressed in HEK293 cell membranes after 60 minsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  53nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053071((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-fluoro-3-methyl...)
Affinity DataKi:  54.3nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053073((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-methoxy-phenyl)...)
Affinity DataKi:  57.4nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088216(CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...)
Affinity DataKi:  59nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088216(CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...)
Affinity DataKi:  59nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053089((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-ethyl-phenyl)-v...)
Affinity DataKi:  82.2nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053075((2S,3S,4S)-4-(1-Biphenyl-3-yl-vinyl)-3-carboxymeth...)
Affinity DataKi:  90.6nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053063((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-methoxy-phenyl)...)
Affinity DataKi:  93.5nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053080((2S,3S,4S)-3-Carboxymethyl-4-[1-(3,4-dimethyl-phen...)
Affinity DataKi:  108nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053083((2S,3S,4S)-3-Carboxymethyl-4-(1-m-tolyl-vinyl)-pyr...)
Affinity DataKi:  123nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053065((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-phenethyloxy-ph...)
Affinity DataKi:  126nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053084((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-methyl-4-phenet...)
Affinity DataKi:  129nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053076((2S,3S,4S)-4-(1-Biphenyl-4-yl-vinyl)-3-carboxymeth...)
Affinity DataKi:  131nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053068((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-isopropenyl-phe...)
Affinity DataKi:  132nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053082((2S,3S,4S)-4-[1-(4-Butyl-phenyl)-vinyl]-3-carboxym...)
Affinity DataKi:  146nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053064((2S,3S,4S)-4-[1-(4-Butoxy-phenyl)-vinyl]-3-carboxy...)
Affinity DataKi:  147nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053059((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-propyl-phenyl)-...)
Affinity DataKi:  147nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088229(2-Amino-4-prop-2-ynyl-pentanedioic acid | CHEMBL59...)
Affinity DataKi:  160nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053062((2S,3S,4S)-3-Carboxymethyl-4-[1-(3,5-dimethyl-phen...)
Affinity DataKi:  169nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053074((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-phenoxy-phenyl)...)
Affinity DataKi:  210nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053060((2S,3S,4S)-4-[1-(4-tert-Butyl-phenyl)-vinyl]-3-car...)
Affinity DataKi:  263nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053079((2S,3S,4S)-4-[1-(3-Butoxy-phenyl)-vinyl]-3-carboxy...)
Affinity DataKi:  275nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053070((2S,3S,4S)-3-Carboxymethyl-4-{1-[4-(1-methylene-pr...)
Affinity DataKi:  288nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088225(CHEMBL58808 | Z-2-Amino-4-(3-phenyl-allyl)-pentane...)
Affinity DataKi:  339nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50089912((2S)-2-amino-4-methylidenepentanedioic acid | 4-me...)
Affinity DataKi:  450nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 2 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088214(2-Amino-4-(2-methyl-3-phenyl-allyl)-pentanedioic a...)
Affinity DataKi:  500nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088205(CHEMBL294683 | E-2-Amino-4-[3-(4-fluoro-phenyl)-al...)
Affinity DataKi:  559nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50116040((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Affinity DataKi:  610nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053086((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-methyl-4-pentyl...)
Affinity DataKi:  663nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053077((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-phenethyloxy-ph...)
Affinity DataKi:  667nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088206(2-Amino-4-prop-2-ynyl-pentanedioic acid | CHEMBL58...)
Affinity DataKi:  823nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50591738(CHEMBL5193862)
Affinity DataKi:  908nMAssay Description:Binding affinity to GluK2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088237(2-Amino-4-(3-phenyl-prop-2-ynyl)-pentanedioic acid...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataKi:  1.11E+3nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 2 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataKi:  1.11E+3nMAssay Description:Binding affinity against human GluR6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088227(CHEMBL58054 | E-2-Amino-4-[3-(3-chloro-phenyl)-all...)
Affinity DataKi:  1.13E+3nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50116043(3-(6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053092((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-methoxy-4-phene...)
Affinity DataKi:  1.28E+3nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50053066((2S,3S,4S)-3-Carboxymethyl-4-{1-[4-(5-phenyl-penty...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 210 total ) | Next | Last >>
Jump to: