Compile Data Set for Download or QSAR
Report error Found 25 of affinity data for UniProtKB/TrEMBL: Q13309
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to human SKP2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258233BDBM50258233(CHEMBL5411495)
Affinity DataIC50: 570nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271727BDBM50271727(CHEMBL5418623)
Affinity DataIC50: 680nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271726BDBM50271726(CHEMBL5420161)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263859BDBM50263859(CHEMBL6102830)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257362BDBM50257362(CHEMBL6078575)
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263858BDBM50263858(CHEMBL6133069)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257360BDBM50257360(CHEMBL6102638)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263857BDBM50263857(CHEMBL5406988)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257309BDBM50257309(CHEMBL6078521)
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622313BDBM50622313(CHEMBL5410031)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257358BDBM50257358(CHEMBL6078063)
Affinity DataIC50: 3.21E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257650BDBM50257650(CHEMBL6083130)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257308BDBM50257308(CHEMBL6102145)
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257359BDBM50257359(CHEMBL6074432)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257363BDBM50257363(CHEMBL5422656)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  4.38E+3nMAssay Description:Binding affinity to human SKP2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263912BDBM50263912(CHEMBL6101857)
Affinity DataIC50: 4.61E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263860BDBM50263860(CHEMBL6132832)
Affinity DataIC50: 4.64E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263913BDBM50263913(CHEMBL6103326)
Affinity DataIC50: 4.64E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257364BDBM50257364(CHEMBL5409004)
Affinity DataIC50: 5.42E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257361BDBM50257361(CHEMBL6078194)
Affinity DataIC50: 6.49E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263914BDBM50263914(CHEMBL5414066)
Affinity DataIC50: 6.65E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622313BDBM50622313(CHEMBL5410031)
Affinity DataIC50: 3.85E+4nMAssay Description:Inhibition of Skp2 in human PC-3 cells treated with shRNA 5'-GGACCTATCGAACTCAGTTAT-3' incubated upto 48 hrs by Western blot analysis (Rvb = 4.8 +/- 0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetS-phase kinase-associated protein 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622313BDBM50622313(CHEMBL5410031)
Affinity DataIC50: 3.92E+4nMAssay Description:Inhibition of Skp2 in human MGC-803 cells treated with shRNA 5'-GGACCTATCGAACTCAGTTAT-3' incubated upto 48 hrs by Western blot analysis (Rvb = 7 +/- ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed