Affinity DataKi: 0.165nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 0.181nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 0.376nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human pyk2More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.683nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.912nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 1.01nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Binding constant for PYK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKi: 1.12nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 1.17nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of full-length PYK2 (unknown origin) with C-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of pyk2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of full-length PYK2 (unknown origin) with C-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.64nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 1.71nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 1.73nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged pyk2 assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
Affinity DataKi: 2.03nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 2.11nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of full-length PYK2 (unknown origin) with C-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.43nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of full-length PYK2 (unknown origin) with C-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.63nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 2.69nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.33nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 3.39nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKd: 3.5nMAssay Description:Binding constant for full-length PTK2BMore data for this Ligand-Target Pair
Affinity DataKd: 3.5nMAssay Description:Binding constant for PYK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.5nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of full-length PYK2 (unknown origin) with C-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.67nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 3.81nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 3.95nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 4.24nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-tagged pyk2 assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
Affinity DataKi: 5.09nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKi: 5.43nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Affinity DataKd: 5.70nMAssay Description:Binding affinity to human recombinant PYK2 (amino acids 420-691) expressed in Escherichia coli, BL21 (DE3) assessed as equilibrium dissociation const...More data for this Ligand-Target Pair
















3D Structure (crystal)





























