Compile Data Set for Download or QSAR
Report error Found 108 of affinity data for UniProtKB/TrEMBL: Q16658
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  19nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526225(CHEMBL4452711)
Affinity DataKd:  50nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526225(CHEMBL4452711)
Affinity DataKd:  90nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526225(CHEMBL4452711)
Affinity DataIC50: 240nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526227(CHEMBL4574198)
Affinity DataKd:  250nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526241(CHEMBL4461540)
Affinity DataKd:  270nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526241(CHEMBL4461540)
Affinity DataIC50: 330nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  348nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526227(CHEMBL4574198)
Affinity DataIC50: 510nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350111(US10208043, # 12 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 539nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350111(US10208043, # 12 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 539nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526226(CHEMBL4559691)
Affinity DataKd:  580nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526240(CHEMBL4566108)
Affinity DataKd:  600nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526226(CHEMBL4559691)
Affinity DataIC50: 630nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526240(CHEMBL4566108)
Affinity DataIC50: 630nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350102(US10208043, # 3 | 2-chloro-N-(6- chlorobenzo[d]thi...)
Affinity DataIC50: 652nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350102(US10208043, # 3 | 2-chloro-N-(6- chlorobenzo[d]thi...)
Affinity DataIC50: 652nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350107(US10208043, # 8 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 683nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350107(US10208043, # 8 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 683nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350100(US10208043, # 1 | 5-(3,4-dichlorobenzyl)-1- (S,S,-...)
Affinity DataIC50: 734nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350100(US10208043, # 1 | 5-(3,4-dichlorobenzyl)-1- (S,S,-...)
Affinity DataIC50: 734nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350109(US10208043, # 10 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 807nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350109(US10208043, # 10 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 807nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350110(US10208043, # 11 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 890nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350110(US10208043, # 11 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 890nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526242(CHEMBL4472315)
Affinity DataKd:  1.03E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526245(CHEMBL4470509)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350120(US10208043, # 21 | 5-(3-chlorobenzyl)-1-(2- hydrox...)
Affinity DataIC50: 1.20E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350120(US10208043, # 21 | 5-(3-chlorobenzyl)-1-(2- hydrox...)
Affinity DataIC50: 1.20E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526230(CHEMBL4457641)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526224(CHEMBL4451624)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526235(CHEMBL4516481)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350108(US10208043, # 9 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 1.47E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350108(US10208043, # 9 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 1.47E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526224(CHEMBL4451624)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526236(CHEMBL4584583)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350112(US10208043, # 13 | (Z)-N-(3-(1H-1,2,4-triazol- 3-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350128(US10208043, # 30 | 5-(3,4-dichlorobenzyl)-1- o-tol...)
Affinity DataIC50: 2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350106(N-phenyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350101(US10208043, # 2 | N-(1-(4- (trifluoromethyl)benzyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350118(US10208043, # 19 | N-(6- chlorobenzo[d]thiazol-2- ...)
Affinity DataIC50: 2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350118(US10208043, # 19 | N-(6- chlorobenzo[d]thiazol-2- ...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350101(US10208043, # 2 | N-(1-(4- (trifluoromethyl)benzyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350106(N-phenyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50: 2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350112(US10208043, # 13 | (Z)-N-(3-(1H-1,2,4-triazol- 3-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50526246(CHEMBL4539975)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
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