Compile Data Set for Download or QSAR
Report error Found 15 of affinity data for UniProtKB/TrEMBL: Q27686
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50597707(CHEMBL5171047)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Leishmania mexicana PYK (Asn75, Il61, Ser362, Arg73, Gln329 residues) incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270352((2S,3S,4S,5R)-N-cycloheptyl-5-((cycloheptylamino)m...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270448((2S,3S,4S,5R)-5-((cycloheptylamino)methyl)-3,4-dih...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270344(2,5-Anhydro-1-deoxy-1-(cycloheptylamino)-D-mannito...)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataKi:  1.16E+5nMAssay Description:Binding affinity to Leishmania mexicana PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270341((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((R)-1-(4-metho...)
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270338((2R,3S,4S,5R)-2-(hydroxymethyl)-5-((1,2,3,4-tetrah...)
Affinity DataIC50: 1.20E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270347((2R,3S,4S,5R)-2-(((1R,2S,4R)-bicyclo[2.2.1]heptan-...)
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270343((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((S)-1-(naphtha...)
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270349((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((R)-1-(naphtha...)
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270345((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((S)-3-methylbu...)
Affinity DataIC50: 2.30E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270474((2R,3S,4S,5R)-2-(hydroxymethyl)-5-((pentan-2-ylami...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270340((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((S)-1-(4-metho...)
Affinity DataIC50: 3.50E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270449((2R,3S,4S,5R)-2-((cyclopentylamino)methyl)-5-(hydr...)
Affinity DataIC50: 4.10E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPyruvate kinase(Leishmania mexicana)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50270339((2R,3S,4S,5R)-2-((cyclobutylamino)methyl)-5-(hydro...)
Affinity DataIC50: 4.30E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed