Compile Data Set for Download or QSAR
Report error Found 4198 of affinity data for UniProtKB/TrEMBL: Q72547
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50002665(6,6,10,11-Tetramethyl-4-propyl-10,11-dihydro-6H-di...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50002662((10R,11S,12S)-12-Hydroxy-6,6,10,11-tetramethyl-4-p...)
Affinity DataEC50:  320nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057014((10R,12R)-12-Hydroxy-6,6,10,11,11-pentamethyl-4-pr...)
Affinity DataEC50:  3.20E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50054452((10R,11R)-6,6,10,11-Tetramethyl-4-propyl-10,11-dih...)
Affinity DataEC50:  4.00E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057028((11S,12S)-12-Hydroxy-6,6,11-trimethyl-4-propyl-11,...)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057037((11R,12R)-12-Hydroxy-6,6,10,10,11-pentamethyl-4-pr...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057029((10R,11S,12S)-10-Ethyl-12-hydroxy-6,6,11-trimethyl...)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057030((10R,11S,12R)-10-Ethyl-12-hydroxy-6,6,11-trimethyl...)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057812(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.30E+4nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057803(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.30E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057809(3-Amino-1-(4-azido-5-hydroxymethyl-tetrahydro-fura...)
Affinity DataEC50:  500nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057819(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.50E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057821([3-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)...)
Affinity DataEC50:  4.70E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057804(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50: >2.90E+4nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057814(2-{2-[3-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataEC50:  1.14E+5nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057818(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  120nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057808(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.43E+5nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057805(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  100nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057810(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  90nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057822(1-(4-azido-5-hydroxymethyltetrahydro-2-furanyl)-3-...)
Affinity DataEC50:  1.40E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057807([3-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)...)
Affinity DataEC50:  1.40E+4nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057811(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.20E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057823(3-Allyl-1-(4-azido-5-hydroxymethyl-tetrahydro-fura...)
Affinity DataEC50:  6.50E+4nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057815(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  1.40E+5nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057816(3-(2-Azido-ethyl)-1-(4-azido-5-hydroxymethyl-tetra...)
Affinity DataEC50:  1.50E+3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50059015([(E)-5-(6-Amino-purin-9-yl)-pent-3-enyloxymethyl]-...)
Affinity DataEC50:  9.00E+3nMAssay Description:tested for its inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50:  1.29E+4nMAssay Description:Cross Resistance (antiviral activity) with K103N (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  1.40E+3nMAssay Description:Cross Resistance (antiviral activity) with A98G (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50: >2.00E+4nMAssay Description:Cross Resistance (antiviral activity) with K101E (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50:  460nMAssay Description:Cross Resistance (antiviral activity) with L74V (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50036504((S-(+))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  200nMAssay Description:Cross Resistance (antiviral activity) with L74V (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  1.63E+4nMAssay Description:Cross Resistance (antiviral activity) with Y181C (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  2.30E+3nMAssay Description:Cross Resistance (antiviral activity) with Y188C (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50: >2.00E+4nMAssay Description:Cross Resistance (antiviral activity) with V106A (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50036504((S-(+))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  1.25E+4nMAssay Description:Cross Resistance (antiviral activity) with V106A (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50:  1.85E+3nMAssay Description:Cross Resistance (antiviral activity) with NL4-3(WT) NNRTI (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  300nMAssay Description:Cross Resistance (antiviral activity) with L100I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  9.70E+3nMAssay Description:Cross Resistance (antiviral activity) with V108I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  1.22E+4nMAssay Description:Cross Resistance (antiviral activity) with L100I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50036504((S-(+))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50: >1.74E+4nMAssay Description:Cross Resistance (antiviral activity) with 4xAZT/L100I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  100nMAssay Description:Cross Resistance (antiviral activity) with L74V (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  700nMAssay Description:Cross Resistance (antiviral activity) with L74V (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50:  1.04E+4nMAssay Description:Cross Resistance (antiviral activity) with V108I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  2.00E+4nMAssay Description:Cross Resistance (antiviral activity) with V106A (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  2.80E+3nMAssay Description:Cross Resistance (antiviral activity) with V108I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate vMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17666(CHEMBL58581 | 2-(2,6-difluorophenyl)-1-[(2,6-diflu...)
Affinity DataEC50:  1.52E+4nMAssay Description:Cross Resistance (antiviral activity) with Y181C (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  1.67E+4nMAssay Description:Cross Resistance (antiviral activity) with K101E (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM17665(CHEMBL293961 | 2-(2,6-difluorophenyl)-1-[(2,6-difl...)
Affinity DataEC50:  8.10E+3nMAssay Description:Cross Resistance (antiviral activity) with K103N (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50036504((S-(+))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  300nMAssay Description:Cross Resistance (antiviral activity) with NL4-3(WT) NNRTI (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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