Compile Data Set for Download or QSAR
Report error Found 15 for UniProtKB: Q78DX7
LigandChemical structure of BindingDB Monomer ID 50653010BDBM50653010(CHEMBL5712062)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of CD74-ROS1 expressed in mouse BaF3 cells assessed as inhibition of phosphorylated ROS1 incubated for 1 hr by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 4552BDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 150nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50436850BDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 1.50E+3nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50384721BDBM50384721(CHEMBL2037224)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50240047BDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50001886BDBM50001886(10-(3-(4-methylpiperazin-1-yl)propyl)-2-(trifluoro...)
Affinity DataIC50: 2.50E+3nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50322823BDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)
Affinity DataIC50: 2.50E+3nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 77970BDBM77970(CLOMIPRAMINE HYDROCHLORIDE | CHLORIMIPRAMINE | 3-(...)
Affinity DataIC50: 3.50E+3nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50384726BDBM50384726(CHEMBL2037208)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50384725BDBM50384725(CHEMBL2037209)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50384727BDBM50384727(CHEMBL2037226)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50384734BDBM50384734(CHEMBL2037211)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50384720BDBM50384720(CHEMBL2037220)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 41585BDBM41585(cid_5759185 | (E)-4,4-dimethyl-1-(3-nitrophenyl)-2...)
Affinity DataIC50: 8.00E+3nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent