Compile Data Set for Download or QSAR
Report error Found 11 of affinity data for UniProtKB/TrEMBL: Q8VHW5
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426093BDBM426093(US10513523, Example 32 | 5-[2-(4-Fluorophenyl)-8-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426073BDBM426073(5-[8-(4-Acetylpiperazin-1-yl)-2-(4-fluorophenyl)im...)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509855BDBM50509855(CHEMBL4545322)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509859BDBM50509859(CHEMBL4458004)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426135BDBM426135(US10513523, Example 74 | 5-[2-(4-Fluorophenyl)-8-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426071BDBM426071(4-[2-(4-Fluorophenyl)-3-(1H-indazol-5-yl)imidazo[1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426098BDBM426098(US10513523, Example 37 | 5-[2-(4-Fluorophenyl)-8-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426069BDBM426069(5-[2-(4-Fluorophenyl)-8-morpholino-imidazo[1,2-a]p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509857BDBM50509857(CHEMBL4474333)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509856BDBM50509856(CHEMBL4533591)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rat)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426144BDBM426144(US10513523, Example 83 | 4-[2-(4-Fluorophenyl)-8-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed