Compile Data Set for Download or QSAR
Report error Found 29 of affinity data for UniProtKB/TrEMBL: Q92835
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610522BDBM50610522(CHEMBL5271592)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of SHIP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365463BDBM50365463(CHEMBL1232461)
Affinity DataKd:  2.65E+3nMAssay Description:Binding affinity against INPP5D (unknown origin) assessed as apparent dissociation constant incubated for 1 hr by colloidal coomassie staining based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657599BDBM50657599(CHEMBL6120493)
Affinity DataKi:  3.20E+3nMAssay Description:Competitive inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells assessed as inhibition constant by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365463BDBM50365463(CHEMBL1232461)
Affinity DataIC50: 4.32E+3nMAssay Description:Inhibition of INPP5D (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657606BDBM50657606(CHEMBL6144748)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of SHIP-1 (unknown origin) by malachite green solution based fluorescence polarization analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657599BDBM50657599(CHEMBL6120493)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657601BDBM50657601(CHEMBL6161781)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657594BDBM50657594(CHEMBL6170714)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657605BDBM50657605(CHEMBL1981401)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of SHIP-1 (unknown origin) using PtdIns(3,4,5)P3 as substrate by malachite green solution based fluorescence polarization analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657590BDBM50657590(CHEMBL1539310)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622455BDBM50622455(CHEMBL5433214)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of SHIP-1 (unknown origin) by malachite green solution based fluorescence polarization analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657602BDBM50657602(CHEMBL6144629)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657607BDBM50657607(CHEMBL6145998)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of SHIP-1 (unknown origin) by malachite green solution based fluorescence polarization analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657593BDBM50657593(CHEMBL6168975)
Affinity DataIC50: 2.34E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657600BDBM50657600(CHEMBL1498430)
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657597BDBM50657597(CHEMBL6148754)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657603BDBM50657603(CHEMBL6144692)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant SHIP-1 (unknown origin) using PtdIns(3,4,5)P3 as substrate incubated for 30 mins by malachite green solution based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657595BDBM50657595(CHEMBL6160481)
Affinity DataIC50: 3.36E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657589BDBM50657589(CHEMBL6152142)
Affinity DataIC50: 3.67E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657591BDBM50657591(CHEMBL6147416)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657592BDBM50657592(CHEMBL6148729)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657598BDBM50657598(CHEMBL6145819)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657596BDBM50657596(CHEMBL6142621)
Affinity DataIC50: 4.02E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 57165BDBM57165(cid_9551168 | MLS000520215 | SMR000130628 | 2-(2-c...)
Affinity DataIC50: 4.66E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657586BDBM50657586(CHEMBL6162681)
Affinity DataIC50: 4.67E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657604BDBM50657604(CHEMBL6160345)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of recombinant SHIP-1 (unknown origin) using PtdIns(3,4,5)P3 as substrate incubated for 30 mins by malachite green solution based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657588BDBM50657588(CHEMBL6102115)
Affinity DataIC50: 6.55E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657587BDBM50657587(CHEMBL6148308)
Affinity DataIC50: 8.68E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50154461BDBM50154461(NCI-303812 | NCI-17383 | 2-[1-(2-Chloro-benzyl)-2-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant SHIP-1 (unknown origin) using PtdIns(3,4,5)P3 as substrate incubated for 30 mins by malachite green solution based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed