Affinity DataIC50: 18nMAssay Description:Inhibitory concentration against caspase-10 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against casp-10 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of caspase-10 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of caspase-10 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of caspase-10 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:The inhibition of the activity of Caspase-1 to -10 by four different compounds (#53, #111, #123 & Z-DEVD-FMK used as a prodrug: z-D(OMe)E(OMe)VD(OMe)...More data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+3nMAssay Description:Inhibition of caspase-10 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of caspase-10 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.33E+3nMAssay Description:The inhibition of the activity of Caspase-1 to -10 by four different compounds (#53, #111, #123 & Z-DEVD-FMK used as a prodrug: z-D(OMe)E(OMe)VD(OMe)...More data for this Ligand-Target Pair
Affinity DataIC50: >3.33E+3nMAssay Description:The inhibition of the activity of Caspase-1 to -10 by four different compounds (#53, #111, #123 & Z-DEVD-FMK used as a prodrug: z-D(OMe)E(OMe)VD(OMe)...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 10 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetCaspase-1/Caspase-10/Caspase-14/Caspase-2/Caspase-3/Caspase-4/Caspase-5/Caspase-6/Caspase-7/Caspase-8/Caspase-9/Inactive caspase-12(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Activation of caspase cascade in human T47D cells using N-(Ac-DEVD)-N'-ethoxycarbonyl-R110 fluorogenic substrate incubated for 48 hrs by fluorescent ...More data for this Ligand-Target Pair