Affinity DataKd: 725nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 10.4nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 1.04E+3nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 104nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 270nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 275nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 130nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 245nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 4.60nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 4.60nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 725nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 270nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 275nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 130nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 245nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 5.90nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 104nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 1.04E+3nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 9nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged TBK1 expressed in baculovirus expression system using CKtide as substrate inc...More data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged TBK1 expressed in baculovirus expression system using CKtide as substrate inc...More data for this Ligand-Target Pair
Affinity DataEC50: 5.39E+4nMAssay Description:Induction of TBK1 in human PBMC assessed as increase in cGAMP secretionMore data for this Ligand-Target Pair
Affinity DataKd: 158nMAssay Description:Binding affinity to TBK1 in human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to TBK1 in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 79nMAssay Description:Binding affinity to TBK1 in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 158nMAssay Description:Binding affinity to phosphorylated TBK1 in calyculin A stimulated human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 32nMAssay Description:Binding affinity to phosphorylated TBK1 in calyculin A stimulated human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Binding affinity to phosphorylated TBK1 in calyculin A stimulated human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to TBK1 in human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to TBK1 in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 251nMAssay Description:Binding affinity to TBK1 in human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 9.30nMAssay Description:Binding affinity to TBK1More data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity to TBK1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TBK1More data for this Ligand-Target Pair
Affinity DataKd: 120nMAssay Description:Binding affinity to TBK1More data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Binding affinity to TBK1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TBK1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TBK1More data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding constant for TBK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.890nMAssay Description:Binding constant for TBK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 9.30nMAssay Description:Binding constant for TBK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Binding constant for TBK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Binding constant for TBK1 kinase domainMore data for this Ligand-Target Pair




























3D Structure (crystal)












