BDBM50327863 (1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate::CHEMBL1258671

SMILES: CCCCN1CCC(COC(=O)c2cc(F)c(N)c3OCCOc23)CC1

InChI Key: InChIKey=WLHFUBIRAHRPHA-UHFFFAOYSA-N

Data: 43 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 44 hits for monomerid = 50327863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.90	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Guinea pig)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		0.334	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Rat)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-1A adrenergic receptor (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		168	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(4) dopamine receptor (Rat)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-2C adrenergic receptor (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		593	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(2) dopamine receptor (Rat)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		615	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-2B adrenergic receptor (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		773	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Rat)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 1D (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		2.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Guinea pig)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		5.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 2C (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		8.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		9.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 5A (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 3A (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1E (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium-dependent serotonin transporter (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Rat)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Rat)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Rat)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Guinea pig)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine receptor H4 (Guinea pig)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Muscarinic acetylcholine receptor M3 (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M4 (Human)	BDBM50327863 ((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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