BDBM14255 4-bromo-3-(carboxymethoxy)-5-[4-(dimethylamino)phenyl]thiophene-2-carboxylic acid::Monocyclic thiophene analog 24
SMILES CN(C)c1ccc(cc1)-c1sc(C(O)=O)c(OCC(O)=O)c1Br
InChI Key InChIKey=VSRQARFUSCWMHO-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 14255
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Miami
Curated by ChEMBL
University Of Miami
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of PTPN1More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nM ΔG°: -8.18kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of PTPN2More data for this Ligand-Target Pair
Affinity DataKi: 9.00E+3nM ΔG°: -6.88kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Miami
Curated by ChEMBL
University Of Miami
Curated by ChEMBL
Affinity DataKi: 6.40E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
University Of Miami
Curated by ChEMBL
University Of Miami
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of PTPRFMore data for this Ligand-Target Pair