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Enter Data

BDBM14605 1-(4-amino-5-chloro-2-methoxyphenyl)-3-(5-cyanopyrazin-2-yl)urea::Chk1_76::N-pyrazinylurea Analog 7

SMILES: COc1cc(N)c(Cl)cc1NC(=O)Nc1cnc(cn1)C#N

InChI Key: InChIKey=DHDDCOYIWRLEJG-UHFFFAOYSA-N

Data: 2 KI 3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14605
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Human)	BDBM14605 (1-(4-amino-5-chloro-2-methoxyphenyl)-3-(5-cyanopyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM14605 (1-(4-amino-5-chloro-2-methoxyphenyl)-3-(5-cyanopyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM14605 (1-(4-amino-5-chloro-2-methoxyphenyl)-3-(5-cyanopyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 [2-280] (Human)	BDBM14605 (1-(4-amino-5-chloro-2-methoxyphenyl)-3-(5-cyanopyr...) Show SMILES Show InChI	GoogleScholar	UniChem		3.93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM14605 (1-(4-amino-5-chloro-2-methoxyphenyl)-3-(5-cyanopyr...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair