BDBM21974 (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid::CHEMBL54976::L-tryptophan::US11021454, Compound L-trp::US9138393, L-Tryptophan::US9144538, L-Tryptophan

SMILES: c1ccc2c(c1)c(c[nH]2)C[C@@H](C(=O)O)N

InChI Key: InChIKey=QIVBCDIJIAJPQS-UHFFFAOYSA-N

Data: 2 KI  13 IC50  1 Kd  1 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 21974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.99E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Large neutral amino acids transporter small subunit 1 (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myeloperoxidase (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Large neutral amino acids transporter small subunit 1 (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (Burkholderia pseudomallei (strain K96243))	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase A-2-activating protein (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Human)	BDBM21974 ((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		1.15E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 21974

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
BDBM36284	BDBM21974				-6.21	3.90	-10.1	4.53	7	25
TBA					Details of this binding reaction